Studying the complex molecular mechanisms involved in traumatic brain injury (TBI) is
crucial for developing new therapies for TBI. Current treatments for TBI are primarily focused …

Background The proteins S100B, neuron-specific enolase (NSE), glial fibrillary acidic
protein (GFAP), ubiquitin carboxy-terminal hydrolase L1 (UCH-L1), and neurofilament light …

Remote ischaemic conditioning (RIC) triggers endogenous protective pathways in distant
organs such as the kidney, heart and brain, and represents an exciting new paradigm in …

Traumatic brain injury (TBI) is a leading cause of mortality and long-term morbidity
worldwide. Despite decades of pre-clinical investigation, therapeutic strategies focused on …

Despite decades of formidable exploration, multi-organ ischemia-reperfusion injury (IRI)
encountered, particularly amongst elderly patients with clinical scenarios, such as age …

Remote ischemic conditioning (RIC) can be effectively applied for cardio-protection. Here, to
clarify whether RIC exerts myocardial protection via aldehyde dehydrogenase 2 (ALDH2) …

Mesenteric ischemia results when there is disruption in blood flow to the small intestine.
Most often, ischemia of the small intestine presents in an acute fashion, though chronic …

Resuscitation induced ischemia/reperfusion predisposes trauma patients to systemic
inflammation and organ dysfunction. We investigated the effect of remote ischemic …

Background Remote ischaemic conditioning (RIC) has been developed as a
neuroprotective strategy to prevent and treat ischaemic stroke. It usually involves restricting …

The pro-inflammatory activity of interleukin 17, which is produced by the IL-23/IL-17 axis, has
been associated with the pathogenesis of traumatic brain injury (TBI). The study investigated …