Orofacial clefts embryology, classification, epidemiology, and genetics

G Nasreddine, J El Hajj… - … Research/Reviews in …, 2021 - Elsevier
Orofacial clefts (OFCs) rank as the second most common congenital birth defect in the
United States after Down syndrome and are the most common head and neck congenital …

[HTML][HTML] Extracellular matrix composition and remodeling: Current perspectives on secondary palate formation, cleft lip/palate, and palatal reconstruction

KBS Paiva, CS Maas, PM Santos… - Frontiers in cell and …, 2019 - frontiersin.org
Craniofacial development comprises a complex process in humans in which failures or
disturbances frequently lead to congenital anomalies. Cleft lip with/without palate (CL/P) is a …

[HTML][HTML] Estimating the birth prevalence and pregnancy outcomes of congenital malformations worldwide

S Moorthie, H Blencowe, MW Darlison, J Lawn… - Journal of community …, 2018 - Springer
Congenital anomaly registries have two main surveillance aims: firstly to define baseline
epidemiology of important congenital anomalies to facilitate programme, policy and …

Global burden of orofacial clefts and the world surgical workforce

BB Massenburg, RA Hopper, CS Crowe… - Plastic and …, 2021 - journals.lww.com
Background: Orofacial clefts are one of the most common congenital anomalies, but this
disease burden is unevenly distributed worldwide. The authors hypothesize that this burden …

[HTML][HTML] Prevalence of non-syndromic orofacial clefts: based on 15,094,978 Chinese perinatal infants

D Fan, S Wu, L Liu, Q Xia, G Tian, W Wang, S Ye… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Non-syndromic orofacial clefts (NSOFC), which include cleft lip and palate (CLP), cleft lip
only (CLO), and cleft palate only (CPO), contains a range of disorders affecting the lips and …

How differences in anatomy and physiology and other aetiology affect the way we label and describe speech in individuals with cleft lip and palate

VJ Pereira, D Sell - International Journal of Language & …, 2023 - Wiley Online Library
Background Speech in individuals with cleft lip and/or palate (CLP) is a complex myriad of
presenting symptoms. It is uniquely associated with the structural difference of …

Global perspectives in orofacial cleft management and research

PA Mossey - British Dental Journal, 2023 - nature.com
Orofacial clefts (OFCs) refer to clefts of the lip and palate, a heterogeneous group of
relatively common congenital conditions that can cause mortality and significant disability if …

[HTML][HTML] Efficacy of recombinant human BMP2 and PDGF-BB in orofacial bone regeneration: a systematic review and meta-analysis

F Li, F Yu, X Liao, C Wu, Y Wang, C Li, F Lou, B Li… - Scientific Reports, 2019 - nature.com
With the rapid development of tissue engineering therapies, there is a growing interest in the
application of recombinant human growth factors (rhGFs) to regenerate human orofacial …

[HTML][HTML] The role of smoke from cooking indoors over an open flame and parental smoking on the risk of cleft lip and palate: A case-control study in 7 low-resource …

A Auslander, R McKean-Cowdin… - Journal of global …, 2020 - ncbi.nlm.nih.gov
Background Cleft is one of the most common birth defects globally and the lack of access to
surgery means millions are living untreated. Smoke exposure from cooking occurs …

[HTML][HTML] The plastic surgery workforce and its role in low-income countries

P Truche, E Moeller, T Wurdeman… - … Surgery–Global Open, 2021 - journals.lww.com
Background: Plastic surgery varies in scope, especially in different settings. This study
aimed to quantify the plastic surgery workforce in low-income countries (LICs), understand …