Mesenchymal stem cells transplantation for perianal fistulas: a systematic review and meta-analysis of clinical trials

H Wang, HY Jiang, YX Zhang, HY Jin, BY Fei… - Stem Cell Research & …, 2023 - Springer
Background Perianal fistulas, characterised as granulomatous inflammation of fistulas
around the anal canal, are associated with significant morbidity resulting in a negative …

The American Society of Colon and Rectal Surgeons clinical practice guidelines for the management of anorectal abscess, fistula-in-ano, and rectovaginal fistula

WB Gaertner, PL Burgess, JS Davids… - Diseases of the Colon …, 2022 - journals.lww.com
(ASCRS) is dedicated to ensuring high-quality patient care by advancing the science and
prevention and management of disorders and diseases of the colon, rectum, and anus. The …

[HTML][HTML] Mesenchymal stem cells for cryptoglandular anal fistula: current state of art

C Eberspacher, D Mascagni, IC Ferent, E Coletta… - Frontiers in …, 2022 - frontiersin.org
Anal fistula is a common disease that needs surgical treatment to be resolved. Despite a
variety of surgical options, the major problem is still to cure complex fistulas without any …

Safety and efficacy of injection of human placenta mesenchymal stem cells derived exosomes for treatment of complex perianal fistula in non‐Crohn's cases: clinical …

H Pak, A Hadizadeh, A Heirani‐Tabasi… - Journal of …, 2023 - Wiley Online Library
Background and Aim A perianal fistula is an abnormal tract that connects anal canal to skin.
Current medical and surgical interventions have a high failure rate particularly in complex …

ADSCs stimulated by VEGF-C alleviate intestinal inflammation via dual mechanisms of enhancing lymphatic drainage by a VEGF-C/VEGFR-3-dependent mechanism …

L Zhang, C Ye, P Li, C Li, W Shu, Y Zhao… - Stem Cell Research & …, 2022 - Springer
Background Adipose-derived stem cells (ADSCs) have provided promising applications for
Crohn's disease (CD). However, the practical efficacy of ADSCs remains controversial, and …

Evaluation of the mechanical properties and clinical application of nickel–titanium shape memory alloy anal fistula clip

H Deng, M Li, X Fang, J Zhang, J Wang, K Tang… - Frontiers in …, 2023 - frontiersin.org
Objective The study investigates the mechanical properties of a nickel–titanium shape
memory alloy anal fistula clip (NiTi-AFC), studies the surgical method of treating anal fistula …

Efficacy and safety of stem cell therapy for Crohn's disease: a meta-analysis of randomized controlled trials

Y Qiu, C Li, S Sheng - Stem Cell Research & Therapy, 2024 - Springer
Purpose Small-scale clinical trials have provided evidence suggesting the effectiveness of
stem-cell therapy (SCT) for patients diagnosed with Crohn's disease (CD). The objective of …

Enhancing surgical precision: unveiling the impact of preoperative colonoscopy in anal fistula patients

S Xu, L Zhang, Z Li, K Wang, F Liu, B Cao - BMC gastroenterology, 2023 - Springer
Background Anal fistula is a common benign anorectal disease that often requires surgical
intervention for effective treatment. In recent years, preoperative colonoscopy as a …

Current Status and Clinical Applications of Tissue Engineering of the Gastrointestinal Tract: A Systematised Narrative Review

Y Liu, L Chong, M Read - Frontiers in Gastroenterology, 2023 - frontiersin.org
Background: Since the advent of regenerative medicine, tissue engineering of the
gastrointestinal tract (GIT) has been extensively studied in laboratory animals and humans …

[HTML][HTML] Efficacy and feasibility of stromal vascular fraction containing adipose derived stem cells obtained from freshly prepared lipoaspirate for treatment of complex …

IF Noori, QK Bakir, AF Noori - International Journal of Surgery Open, 2023 - Elsevier
Background Anal fistulas are relatively common. Despite diverse treatment modalities and
tremendous advance and optimization of surgical approaches, considerable recurrence and …