Cerebral autoregulation, spreading depolarization, and implications for targeted therapy in brain injury and ischemia

AP Carlson, AR Mayer, C Cole… - Reviews in the …, 2024 - degruyter.com
Cerebral autoregulation is an intrinsic myogenic response of cerebral vasculature that
allows for preservation of stable cerebral blood flow levels in response to changing systemic …

Does the Ischemic Core Really Matter? An Updated Systematic Review and Meta‐Analysis of Large Core Trials After TESLA, TENSION, and LASTE

M AlMajali, M Dibas, M Ghannam… - Stroke: Vascular and …, 2024 - Am Heart Assoc
Background The available evidence supporting the use of endovascular thrombectomy
(EVT) in acute ischemic stroke patients with large core has increased with the recent release …

The impact of large core and late treatment trials: An update on the modelled annual thrombectomy eligibility of UK stroke patients

P McMeekin, M James, CI Price… - European Stroke …, 2024 - journals.sagepub.com
Introduction: To support decisions about thrombectomy provision, we have previously
estimated the annual UK population eligible for treatment as∼ 10% of stroke admissions …

Neuroendovascular Rescue 2025: Trends in Stroke Endovascular Therapy

CR Gomez, BR French, FE Gomez… - Neurologic …, 2024 - neurologic.theclinics.com
The emergent endovascular management of patients with acute ischemic stroke (AIS)
caused by a large arterial occlusion (LAO) exploded following the 2015 publication of pivotal …

Imaging in acute ischaemic stroke: assessing findings in light of evolving therapies

P Frias, RS Khangura, B Varjavand… - British Journal of …, 2024 - academic.oup.com
Acute ischaemic stroke (AIS) is a debilitating disease for which effective therapies are now
available. Effective identification of candidates for therapy relies heavily on noninvasive …

Blood glucose to predict symptomatic intracranial hemorrhage after endovascular treatment of acute ischemic stroke with large infarct core: a prospective …

Y Yang, L Yang, X Shi, X Ni, S Fan, X Xu, J Ma… - Frontiers in …, 2024 - frontiersin.org
Introduction Symptomatic intracranial hemorrhage (sICH) is a serious complication of acute
ischemic stroke (AIS) after endovascular treatment (EVT). Limited data exist regarding …

Endovascular thrombectomy for acute ischemic stroke with a large infarct area: an updated systematic review and meta-analysis of randomized controlled trials

S Ravipati, A Amjad, K Zulfiqar, H Biju… - Journal of Stroke and …, 2024 - Elsevier
Background Since the efficacy and safety of endovascular thrombectomy (EVT) in patients
with acute ischemic stroke with a large infarct area is still inconclusive, we sought to …

Revolutionizing the Management of Large-Core Ischaemic Strokes: Decoding the Success of Endovascular Therapy in the Recent Stroke Trials

GZ Lim, JY Lai, CYH Seet, CH Tham… - Journal of …, 2023 - mdpi.com
Endovascular therapy (EVT) has revolutionized the management of acute ischaemic strokes
with large vessel occlusion, with emerging evidence suggesting its benefit also in large …

[HTML][HTML] Mechanical Thrombectomy in Ischemic Stroke with a Large Infarct Core: A Meta-Analysis of Randomized Controlled Trials

M Romoli, L Princiotta Cariddi, M Longoni… - Journal of Clinical …, 2024 - mdpi.com
Background/Objectives: Endovascular treatment (EVT) is recommended for acute ischemic
stroke due to large-vessel occlusion (LVO) and an Alberta Stroke Program Early CT Score …

2023 neurocritical care updates in cerebrovascular disease

RM Jha, KN Sheth - Stroke, 2023 - Am Heart Assoc
ANGEL-ASPECT randomized 456 patients in China (ASPECTS, 3–5 or infarct, 70–100 mL)
within 24 hours of last known well to either EVT or medical management. The second interim …