Angiogenesis has become an attractive target for drug therapy because of its key role in
tumor growth. An extensive array of compounds is currently in preclinical development, with …

Treatment of squamous cell carcinoma of the head and neck (SCCHN) has evolved greatly
in the last two decades, owing to the integration of chemotherapy, advances in …

A major challenge in photodynamic cancer therapy (PDT) is avoiding PDT-induced hypoxia,
which can lead to cancer recurrence and progression through activation of various …

Background: Angiogenesis (formation of new blood vessels) is associated with tumor growth
and metastasis in patients with solid tumors, including those of the head and neck. Nitric …

BACKGROUND Vascular endothelial growth factor (VEGF), a recently identified growth
factor with significant angiogenic properties, is a multifunctional angiogenic cytokine that is …

To investigate the clinical significance of vascular endothelial growth factor (VEGF) in
osteosarcoma, we immunohistochemically stained biopsy specimens of 27 primary …

As in other tumors, the assessment of microvessel density (MVD) in hepatocellular
carcinoma (HCC) may be essential to perform an effective anti-angiogenic therapy for this …

We evaluated the role of COX-2 pathway in 35 head and neck cancers (HNCs) by analyzing
COX-2 expression and prostaglandin E 2 (PGE 2) production in relation to tumor …

Vascular endothelial growth factor (VEGF) may affect the phenotype of cancer cells, such as
growth velocity and metastatic potential, due to its probable multifunctional property …

Aims: Angiogenesis is a complex multistep process essential for tumour growth. Vascular
endothelial growth factor (VEGF) is a potent endothelial cell mitogen and vascular …