[HTML][HTML] X-ray dark-field chest imaging for detection and quantification of emphysema in patients with chronic obstructive pulmonary disease: a diagnostic accuracy …

K Willer, AA Fingerle, W Noichl, F De Marco… - The Lancet Digital …, 2021 - thelancet.com
Background Although advanced medical imaging technologies give detailed diagnostic
information, a low-dose, fast, and inexpensive option for early detection of respiratory …

Three-dimensional visualisation of soft biological structures by X-ray computed micro-tomography

T Shearer, RS Bradley… - Journal of cell …, 2016 - journals.biologists.com
Whereas the two-dimensional (2D) visualisation of biological samples is routine, three-
dimensional (3D) imaging remains a time-consuming and relatively specialised pursuit …

[HTML][HTML] Advanced imaging in COPD: insights into pulmonary pathophysiology

S Milne, GG King - Journal of thoracic disease, 2014 - ncbi.nlm.nih.gov
Chronic obstructive pulmonary disease (COPD) involves a complex interaction of structural
and functional abnormalities. The two have long been studied in isolation. However …

X-ray dark-field chest imaging: qualitative and quantitative results in healthy humans

FT Gassert, T Urban, M Frank, K Willer, W Noichl… - Radiology, 2021 - pubs.rsna.org
Background X-ray dark-field radiography takes advantage of the wave properties of x-rays,
with a relatively high signal in the lungs due to the many air-tissue interfaces in the alveoli …

[HTML][HTML] In-vivo dark-field and phase-contrast x-ray imaging

M Bech, A Tapfer, A Velroyen, A Yaroshenko… - Scientific reports, 2013 - nature.com
Novel radiography approaches based on the wave nature of x-rays when propagating
through matter have a great potential for improved future x-ray diagnostics in the clinics …

[HTML][HTML] X-ray dark-field imaging of the human lung—A feasibility study on a deceased body

K Willer, AA Fingerle, LB Gromann, F De Marco… - PloS one, 2018 - journals.plos.org
Disorders of the lungs such as chronic obstructive pulmonary disease (COPD) are a major
cause of chronic morbidity and mortality and the third leading cause of death in the world …

[HTML][HTML] In-vivo x-ray dark-field chest radiography of a pig

LB Gromann, F De Marco, K Willer, PB Noël… - Scientific reports, 2017 - nature.com
X-ray chest radiography is an inexpensive and broadly available tool for initial assessment
of the lung in clinical routine, but typically lacks diagnostic sensitivity for detection of …

[HTML][HTML] On the quantification of sample microstructure using single-exposure x-ray dark-field imaging via a single-grid setup

YY How, DM Paganin, KS Morgan - Scientific Reports, 2023 - nature.com
The size of the smallest detectable sample feature in an x-ray imaging system is usually
restricted by the spatial resolution of the system. This limitation can now be overcome using …

[HTML][HTML] X-ray Dark-field Radiography - In-Vivo Diagnosis of Lung Cancer in Mice

K Scherer, A Yaroshenko, DA Bölükbas, LB Gromann… - Scientific reports, 2017 - nature.com
Accounting for about 1.5 million deaths annually, lung cancer is the prevailing cause of
cancer deaths worldwide, mostly associated with long-term smoking effects. Numerous …

[HTML][HTML] Improved In vivo Assessment of Pulmonary Fibrosis in Mice using X-Ray Dark-Field Radiography

A Yaroshenko, K Hellbach, AÖ Yildirim, TM Conlon… - Scientific reports, 2015 - nature.com
Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease with a median
life expectancy of 4–5 years after initial diagnosis. Early diagnosis and accurate monitoring …