Objective: We reviewed important clinical aspects of bipolar depression, a progressive
psychiatric condition that is commonly treated in primary care. Bipolar depression is …

Objective: We examined the influence of age at onset of illness and the delay in time to first
treatment on morbidity in adulthood. Method: 529 adult outpatients with a mean age of 42 …

Novick DM, Swartz HA, Frank E. Suicide attempts in bipolar I and bipolar II disorder: a review
and metaanalysis of the evidence. Bipolar Disord 2010: 12: 1–9.© 2010 The Authors …

There is a great deal of research on the prevalence, correlates, and treatment of PTSD in the
general population. However, we know very little about the manifestation and consequences …

Objectives: This review summarizes the literature on psychiatric and medical comorbidities
in bipolar disorder. The coexistence of other Axis I disorders with bipolar disorder …

BackgroundFew investigations have examined the impact of childhood trauma, and
domains of childhood abuse, on outcome in bipolar disorder. AimsTo evaluate the …

Objective: To determine the main risk factors for suicide and nonfatal suicidal behavior in
patients with bipolar disorder through a systematic review of the international literature. Data …

In the majority of patients with mood disorders, suicidal behaviour is predictable and
preventable, with a good chance. A careful and systematic exploration of suicide risk factors …

Objective Few studies have been reported that support the efficacy of adjunctive therapy for
patients with bipolar I depression who have had an insufficient response to monotherapy …

DaruyFilho L, Brietzke E, Lafer B, GrassiOliveira R. Childhood maltreatment and clinical
outcomes of bipolar disorder. Objective: Adverse life events, especially early trauma, play a …