Vascular contributions to cognitive impairment and dementia, specifically cerebral small
vessel disease (CSVD), are the second most common cause of dementia. Currently, there …

BACKGROUND: Regular exercise has been recommended clinically for all individuals to
protect against hypertension but the underlying mechanisms are not fully elucidated. We …

This study aimed to compare the effect of high-intensity interval training (HIIT) with moderate-
intensity continuous training (MCT) on endothelial function, oxidative stress and clinical …

To determine if age-associated vascular dysfunction in older adults with heart failure (HF) is
due to insufficient synthesis of nitric oxide (NO), we performed two separate studies: 1) a …

Management of hypertension and prevention of cognitive decline are challenging public
health problems. However, the effects of exergame intervention on blood pressure (BP) …

Aging results in functional and structural changes in the cardiovascular system, translating
into a progressive increase of mechanical vessel stiffness, due to a combination of changes …

There is an emerging body of literature relating to the effectiveness of frequent aerobic
exercise as a prophylactic for age-associated dysfunction of large arteries, yet systematic …

Background Blood flow restricted exercise (BFRE) improves physical fitness, with theorized
positive effects on vascular function. This systematic review and meta-analysis aimed to …

Background Adropin is a peptide hormone that promotes nitric oxide (NO) production via
activation of endothelial NO synthase (eNOS) in endothelial cells. Its circulating levels are …

The objective of this systematic review was to examine the effects of exercise training on
endothelial function in individuals with overweight and obesity. Our review study included …