Pathophysiology of atherosclerosis
S Jebari-Benslaiman, U Galicia-García… - International journal of …, 2022 - mdpi.com
Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …
Foam cells in atherosclerosis: novel insights into its origins, consequences, and molecular mechanisms
Y Gui, H Zheng, RY Cao - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Foam cells play a vital role in the initiation and development of atherosclerosis. This review
aims to summarize the novel insights into the origins, consequences, and molecular …
aims to summarize the novel insights into the origins, consequences, and molecular …
Macrophages in cardiac remodelling after myocardial infarction
J Yap, J Irei, J Lozano-Gerona, S Vanapruks… - Nature Reviews …, 2023 - nature.com
Myocardial infarction (MI), as a result of thrombosis or vascular occlusion, is the most
prevalent cause of morbidity and mortality among all cardiovascular diseases. The …
prevalent cause of morbidity and mortality among all cardiovascular diseases. The …
Oxidative stress is a key modulator in the development of nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease
worldwide, and scientific studies consistently report that NAFLD development can be …
worldwide, and scientific studies consistently report that NAFLD development can be …
Mechanisms of foam cell formation in atherosclerosis
DA Chistiakov, AA Melnichenko… - Journal of molecular …, 2017 - Springer
Low-density lipoprotein (LDL) and cholesterol homeostasis in the peripheral blood is
maintained by specialized cells, such as macrophages. Macrophages express a variety of …
maintained by specialized cells, such as macrophages. Macrophages express a variety of …
Atherosclerosis and inflammation: insights from the theory of general pathological processes
E Gusev, A Sarapultsev - International Journal of Molecular Sciences, 2023 - mdpi.com
Recent advances have greatly improved our understanding of the molecular mechanisms
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …
behind atherosclerosis pathogenesis. However, there is still a need to systematize this data …
Macrophage plasticity and atherosclerosis therapy
P Lin, HH Ji, YJ Li, SD Guo - Frontiers in molecular biosciences, 2021 - frontiersin.org
Atherosclerosis is a chronic disease starting with the entry of monocytes into the
subendothelium and the subsequent differentiation into macrophages. Macrophages are the …
subendothelium and the subsequent differentiation into macrophages. Macrophages are the …
Soluble epoxide hydrolase: a potential target for metabolic diseases: 可溶性表氧化物酶: 代谢性疾病的潜在治疗靶点
摘要环氧‐二十碳三烯酸(Epoxyeicosatrienoic acids, EET) 是花生四烯酸的重要代谢产物. EET
在包括动脉粥样硬化, 高血压, 心脏纤维化, 糖尿病, 非酒精性脂肪肝以及肾脏疾病在内的诸多 …
在包括动脉粥样硬化, 高血压, 心脏纤维化, 糖尿病, 非酒精性脂肪肝以及肾脏疾病在内的诸多 …
Macrophage‐mediated cholesterol handling in atherosclerosis
DA Chistiakov, YV Bobryshev… - Journal of cellular and …, 2016 - Wiley Online Library
Formation of foam cells is a hallmark at the initial stages of atherosclerosis. Monocytes
attracted by pro‐inflammatory stimuli attach to the inflamed vascular endothelium and …
attracted by pro‐inflammatory stimuli attach to the inflamed vascular endothelium and …
Through the layers: how macrophages drive atherosclerosis across the vessel wall
LI Susser, KJ Rayner - The Journal of clinical investigation, 2022 - Am Soc Clin Investig
Cardiovascular disease (CVD) accounts for almost half of all deaths related to non-
communicable disease worldwide, making it the single largest global cause of mortality …
communicable disease worldwide, making it the single largest global cause of mortality …