Subcortical dementia refers to a clinical syndrome characterised by slowing of cognition,
memory disturbances, difficulty with complex intellectual tasks such as strategy generation …

PERHAPS the greatest focus of attention in recent years regarding the functions of the basal
ganglia (ie caudate nucleus, putamen, globus pallidus and substantia nigra) has been given …

Abstract Changes in the cholinergic, serotonergic, noradrenergic, dopaminergic, GABAergic
and somatostatinergic neurons were investigated to determine their roles in Alzheimer's …

Nicotinic and muscarinic cholinergic receptors were studied in autopsied brains from four
histologically normal controls and five histopathologically verified cases of Alzheimertype …

Abstract [3 H] Quinuclidinylbenzilate ([3 H] QNB) binding and choline acetyltransferase
(CAT) activity were studied in post-mortem brains from control and Parkinsonian subjects …

Using radioligand binding techniques, we determined the equilibrium dissociation constants
(K D's) for a series of neuroleptics at the dopamine (D-2), muscarinic, histamine H 1, α 1-and …

The technique of quantitative autoradiography was used to examine the effects of
Huntington's disease (HD) and schizophrenia on the organization of striatal dopamine (DA) …

A radioiodinated ligand that binds to muscarinic acetylcholine receptors was shown to
distribute in the brain by a receptor-mediated process. With single-photon-emission imaging …

Vulnerability of neurotransmitterspecific neurons to hypoxiaischemia was examined in the
immature rat corpus striatum. Carotid artery ligation plus 2 hours of 8% oxygen atmosphere …

Mapping of a number of biochemical markers for noradrenergic, dopaminergic,
serotoninergic, cholinergic and GABAergic systems was undertaken in 93 samples removed …