Characterization of muscarinic cholinergic receptors in the lower esophageal sphincter of the cat: binding of [3H] quinuclidinyl benzilate

TJ Rimele, WA Rogers, TS Gaginella - Gastroenterology, 1979 - Elsevier
We have studied the binding of the potent muscarinic antagonist [3 H] quinuclidinyl benzilate
to characterize muscarinic receptors in the lower esophageal sphincter of the cat. Specific …

Quantitative light microscopic autoradiographic localization of cholinergic muscarinic receptors in the human brain: forebrain

R Corte, A Probst, JM Palacios - Neuroscience, 1987 - Elsevier
The distribution of muscarinic cholinergic receptors in the human forebrain and cerebellum
was studied in detail by quantitative autoradiography using N-[3 H] methylscopolamine as a …

Cholinergic binding sites with muscarinic properties on membranes from the supraoesophageal ganglion of the locust (Schistocerca gregaria)

JS Aguilar, GG Lunt - Neurochemistry international, 1984 - Elsevier
A crude membrane preparation from the supraoesophageal ganglion of the locust
(Schistocerca gregaria) shows specific binding of muscarinic cholinergic ligands. Analysis of …

beta-RTX. A receptor-active protein from Russell's viper (Vipera russelli russelli) venom.

P Bevan, P Hiestand - Journal of Biological Chemistry, 1983 - ASBMB
A single chain polypeptide, termed beta-RTX, with an apparent Mr= 9600 has been isolated
from the venom of Vipera russelli russelli. It was purified by cation exchange …

Effects of recombinant interleukin 1 and interleukin 2 on human keratinocytes

VB Morhenn, GJ Wastek, AB Cua… - Journal of investigative …, 1989 - Elsevier
The effects of recombinant interleukin 1 alpha and beta, as well as recombinant interleukin
2, on human keratinocyte proliferation were studied in serum-containing as well as defined …

Binding studies with [3H]cis-methyldioxolane in different tissues: Under certain conditions [3H]cis-methyldioxolane labels preferentially but not exclusively agonist high affinity …

A Closse, H Bittiger, D Langenegger… - … archives of pharmacology, 1987 - Springer
Special conditions-tricine buffer containing Ca 2+ and Mg 2+, 22° C (TCM)—allow to label a
much higher proportion of muscarinic receptors by [3 H] cis-methyldioxolane (CD) than …

Pharmacological analysis of the muscarinic receptors involved when McNA 343 stimulates acid secretion in the mouse isolated stomach

JW Black, NP Shankley - British journal of pharmacology, 1985 - Wiley Online Library
1 In view of the recent M1 and M2 subclassification of muscarinic receptors and the
suggestion of separate populations of muscarinic receptors on oxyntic and histamine cells in …

Choline: binding studies provide some evidence for a weak, direct agonist action in brain

JM PALACIOS, MJ KUHAR - Molecular Pharmacology, 1979 - ASPET
The potential ability of choline to act as a muscarinic agonist in brain was examined. Binding
curves for muscarinic agonists are flattened and their Hill coefficients are lower than unity …

Postmortem changes in binding to the muscarinic receptor from human cerebral cortex

A Unden, B Meyerson, B Winblad… - Journal of …, 1983 - Wiley Online Library
The effects of storage at 4° C on the antagonist and agonist binding properties of the
muscarinic acetylcholine receptor from fresh surgical and frozen autopsy samples from …

Quaternary ammonium salts—advances in chemistry and pharmacology since 1960

B Berde, CJ Cavallito, IM Hunneyball, S Sharma… - Progress in Drug …, 1980 - Springer
Twenty years ago there appeared in this review series a chapter entitled,'Chemical Nature
and Pharmacological Actions of Quaternary Ammonium Salts'[1]. The present treatment …