Oxygen, early embryonic metabolism and free radical-mediated embryopathies

GJ Burton, J Hempstock, E Jauniaux - Reproductive biomedicine online, 2003 - Elsevier
Free radicals, once the preserve of chemists, are now recognized as playing a central role in
many biological systems. They are formed as an inevitable by-product of aerobic respiration …

Time-lapse technology for embryo culture and selection

K Lundin, H Park - Upsala journal of medical sciences, 2020 - Taylor & Francis
Culturing of human embryos in optimal conditions is crucial for a successful in vitro
fertilisation (IVF) programme. In addition, the capacity to assess and rank embryos correctly …

[HTML][HTML] In vitro fertilization (IVF) in mammals: epigenetic and developmental alterations. Scientific and bioethical implications for IVF in humans

P Ventura-Juncá, I Irarrázaval, AJ Rolle, JI Gutiérrez… - Biological Research, 2015 - Springer
The advent of in vitro fertilization (IVF) in animals and humans implies an extraordinary
change in the environment where the beginning of a new organism takes place. In mammals …

Embryo culture systems

DK Gardner, M Lane - In Vitro Fertilization, 2006 - taylorfrancis.com
The success of clinical IVF was initially compromised by sub-optimal culture conditions,
resulting in impaired embryo development (1–6) and a subsequent loss of viability …

Type of culture media does not affect embryo kinetics: a time-lapse analysis of sibling oocytes

N Basile, D Morbeck, J García-Velasco… - Human …, 2013 - academic.oup.com
STUDY QUESTION Are the morphokinetics of growing embryos affected by the type of
culture media utilized? SUMMARY ANSWER Morphokinetic parameters used for embryo …

[HTML][HTML] Choosing a culture medium: making informed choices

JD Biggers, MC Summers - Fertility and sterility, 2008 - Elsevier
OBJECTIVE: To analyze critically the reasons justifying the choice of two-step protocols
requiring two media for the culture of human preimplantation embryos from the zygote to the …

Towards a single embryo transfer

DK Gardner, M Lane - Reproductive BioMedicine Online, 2003 - Elsevier
The delivery of a single, healthy child is the desired outcome of human assisted
reproduction techniques. To attain this goal, there is an increasing movement toward single …

The Well-of-the-Well system: an efficient approach to improve embryo development

G Vajta, T Korösi, Y Du, K Nakata, S Ieda… - Reproductive …, 2008 - Elsevier
Transfer of human embryos at the blastocyst stage may offer considerable benefits including
an increased implantation rate and a decreased risk of multiple pregnancies; however …

Advances in embryo culture platforms: novel approaches to improve preimplantation embryo development through modifications of the microenvironment

JE Swain, GD Smith - Human reproduction update, 2011 - academic.oup.com
BACKGROUND The majority of research aimed at improving embryo development in vitro
has focused on manipulation of the chemical environment, examining details such as …

Impact of oxygen concentration on embryonic development of mouse zygotes

L Karagenc, Z Sertkaya, N Ciray, U Ulug… - Reproductive …, 2004 - Elsevier
The aim of the present study was to examine the effect of culture under 5 and 20% oxygen
on the development, differentiation and viability of zygotes and in-vivo-produced embryos at …