Zebrafish (Danio rerio) are a small‐bodied tropical, freshwater fish species originally from
South Asia. The ease of care, year‐round prolific breeding, and transparent, external …

The zebrafish model is the only available high-throughput vertebrate assessment system,
and it is uniquely suited for studies of in vivo cell biology. A sequenced and annotated …

The mechanistic target of rapamycin complex 1 (mTORC1) is a key metabolic hub that
controls the cellular response to environmental cues by exerting its kinase activity on …

High-throughput mapping of cellular differentiation hierarchies from single-cell data
promises to empower systematic interrogations of vertebrate development and disease …

INTRODUCTION The ability to regenerate tissues lost to damage or disease is widely but
nonuniformly distributed in vertebrates. Some animals such as teleost fishes can regenerate …

We report the evolution of mScarlet3, a cysteine-free monomeric red fluorescent protein with
fast and complete maturation, as well as record brightness, quantum yield (75%) and …

INTRODUCTION The developmental path by which a fertilized egg gives rise to the cells of a
multicellular organism is termed the cell lineage. In 1983, John Sulston and colleagues …

Cultured stem cells have become a standard platform not only for regenerative medicine
and developmental biology but also for biophysical studies. Yet, the characterization of …

To enable rapid propagation of action potentials, axons are ensheathed by myelin, a
multilayered insulating membrane formed by oligodendrocytes. Most of the myelin is …

The intestinal epithelium senses nutritional and microbial stimuli using epithelial sensory
enteroendocrine cells (EEC). EECs communicate nutritional information to the nervous …