Evaluation of NG-Test CARBA 5 version 2, Cepheid Xpert Carba-R, and carbapenem inactivation methods in comparison to whole-genome sequencing for the …

BY Khoo, PY Hon, J Leong… - Journal of Clinical …, 2023 - Am Soc Microbiol
ABSTRACT NG-Test CARBA 5 (NG-Biotech) is a rapid in vitro multiplex immunoassay for
the phenotypic detection and differentiation of the “big five” carbapenemase families (KPC …

KPC-53, a KPC-3 variant of clinical origin associated with reduced susceptibility to ceftazidime-avibactam

V Di Pilato, N Aiezza, V Viaggi, A Antonelli… - Antimicrobial Agents …, 2020 - Am Soc Microbiol
This study reports on the characterization of a Klebsiella pneumoniae clinical isolate
showing high-level resistance to ceftazidime-avibactam associated with the production of …

Development of microfluidic chip-based loop-mediated isothermal amplification (LAMP) method for detection of carbapenemase producing bacteria

B Wu, X Tong, B Chen, W Yuan, M Fu… - Microbiology …, 2022 - Am Soc Microbiol
The rapid and accurate diagnostic methods to identify carbapenemase-producing
organisms (CPO) is of great importance for controlling the CPO infection. Herein, we have …

The present danger of New Delhi metallo-β-lactamase: A threat to public health

M Usman Qamar, BS Lopes, B Hassan… - Future …, 2020 - Taylor & Francis
The evolution of antimicrobial-resistant Gram-negative pathogens is a substantial menace to
public health sectors, notably in developing countries because of the scarcity of healthcare …

[HTML][HTML] Carbapenemase detection by NG-Test CARBA 5—a rapid immunochromatographic assay in carbapenem-resistant Enterobacterales diagnosis

Y Zhu, P Jia, X Li, T Wang, J Zhang… - Annals of …, 2021 - ncbi.nlm.nih.gov
Background The global spread of carbapenem-resistant Enterobacterales (CRE) represents
a serious public health concern as these organisms are associated with limited treatment …

Performance comparison of BD Phoenix CPO detect panel with Cepheid Xpert Carba-R assay for the detection of carbapenemase-producing Klebsiella pneumoniae …

NÜ Tüzemen, U Önal, O Merdan, B Akca, B Ener… - BMC microbiology, 2024 - Springer
Background We aimed to compare the performance of carbapenemase classification in
carbapenem-resistant Klebsiella pneumoniae (CRKP) obtained using the BD Phoenix CPO …

Using molecular diagnostics to develop therapeutic strategies for carbapenem-resistant Gram-negative infections

FC Tenover - Frontiers in cellular and infection microbiology, 2021 - frontiersin.org
Infections caused by multidrug-resistant Gram-negative organisms have become a global
threat. Such infections can be very difficult to treat, especially when they are caused by …

Emergence of pandrug-resistant carbapenemase-producing Enterobacterales in dogs and cats: a cross-sectional study in Egypt

YH Tartor, AM Ammar, A Abdelkhalek… - Frontiers in cellular …, 2024 - frontiersin.org
One of the most important emerging health problems is the increasing role of animals in the
rapid global rise in resistance to last-resort antibiotics, such as carbapenems. However …

Clinical and molecular epidemiology of carbapenem-resistant Enterobacteriaceae in pediatric inpatients in South China

Z Xiong, C Zhang, K Sarbandi, Z Liang, J Mai… - Microbiology …, 2023 - Am Soc Microbiol
Carbapenem-resistant Enterobacteriaceae (CRE) are a substantial health burden. Existing
management guidelines are primarily based on clonal evidence. Therefore, epidemiological …

Antimicrobial and Diagnostic Stewardship of the Novel β-Lactam/β-Lactamase Inhibitors for Infections Due to Carbapenem-Resistant Enterobacterales Species and …

S Ferous, C Anastassopoulou, V Pitiriga, G Vrioni… - Antibiotics, 2024 - mdpi.com
Carbapenem-resistant Gram-negative bacterial infections are a major public health threat
due to the limited therapeutic options available. The introduction of the new β-lactam/β …