Bacterial resistance to antibiotics and clonal spread in COVID-19-positive patients on a tertiary hospital intensive care unit, Czech Republic

L Doubravská, M Htoutou Sedláková, K Fišerová… - Antibiotics, 2022 - mdpi.com
This observational retrospective study aimed to analyze whether/how the spectrum of
bacterial pathogens and their resistance to antibiotics changed during the worst part of the …

Performance Evaluation of the MBT STAR®-Carba IVD Assay for the Detection of Carbapenemases With MALDI-TOF MS

A Anantharajah, B Tossens, N Olive… - Frontiers in …, 2019 - frontiersin.org
Objectives: The increasing rate of carbapenem resistance in Gram-negative bacteria is a
major public health problem and rapid detection is essential for infection management. We …

Precision medicine for the diagnosis and treatment of carbapenem-resistant Enterobacterales: time to think from a different perspective

S Reyes, DP Nicolau - Expert Review of Anti-Infective Therapy, 2020 - Taylor & Francis
ABSTRACT Introduction Carbapenem-resistant Enterobacterales (CRE) represent a global
public health problem. Precision medicine (PM) is a multicomponent medical approach that …

[HTML][HTML] Carbapenemase-producing Enterobacteriaceae: A diagnostic, epidemiological and therapeutic challenge

MV Villegas, A Jiménez, G Esparza, TM Appel - Infectio, 2019 - scielo.org.co
The global spread of carbapenemase-producing Enterobacteriaceae (CPE) has become a
public health problem. Not all CPE are resistant to carbapenems creating a diagnostic and …

The Likelihood of Developing a Carbapenem-Resistant Enterobacteriaceae Infection during a Hospital Stay

PD Tamma, A Kazmi, Y Bergman… - Antimicrobial agents …, 2019 - Am Soc Microbiol
Of 1,455 unique patients in US intensive care units (ICUs), 4% were rectally colonized with
CRE on admission. A total of 297 patients were initially negative for carbapenem-resistant …

Comparison of two multiplex immunochromatographic assays for the rapid detection of major carbapenemases in Enterobacterales

P Bogaerts, AS Berger, S Evrard… - Journal of Antimicrobial …, 2020 - academic.oup.com
Objectives Two commercially available lateral flow immunochromatographic assays (ICAs)
for detection of the major carbapenemases were prospectively assessed for the detection of …

Molecular Characterization of Carbapenem Resistant Klebsiella pneumoniae in Malaysia Hospital

MY Lau, FE Teng, KH Chua, S Ponnampalavanar… - Pathogens, 2021 - mdpi.com
The emergence of carbapenem-resistant Klebsiella pneumoniae (CRKP) is a great concern,
as carbapenems are the last-line therapy for multidrug-resistant Gram-negative bacteria …

Evaluation of NG-Test CARBA 5 version 2, Cepheid Xpert Carba-R, and carbapenem inactivation methods in comparison to whole-genome sequencing for the …

BY Khoo, PY Hon, J Leong… - Journal of Clinical …, 2023 - Am Soc Microbiol
ABSTRACT NG-Test CARBA 5 (NG-Biotech) is a rapid in vitro multiplex immunoassay for
the phenotypic detection and differentiation of the “big five” carbapenemase families (KPC …

Application of a multiplex immunochromatographic assay for rapid identification of carbapenemases in a clinical microbiology laboratory: performance and turn …

J Yoon, CH Kim, SY Yoon, CS Lim, CK Lee - BMC microbiology, 2021 - Springer
Background Prompt and accurate identification of carbapenemase production is essential
for appropriate treatment and infection control. NG-Test Carba 5 (termed herein “Carba 5”; …

[HTML][HTML] Accurate detection of the four most prevalent carbapenemases in E. coli and K. pneumoniae by high-resolution mass spectrometry

DE Foudraine, LJM Dekker, N Strepis… - Frontiers in …, 2019 - frontiersin.org
Background At present, phenotypic growth inhibition techniques are used in routine
diagnostic microbiology to determine antimicrobial resistance of bacteria. Molecular …