Regulation of Staphylococcus aureus Virulence

C Jenul, AR Horswill - Microbiology spectrum, 2019 - Am Soc Microbiol
Staphylococcus aureus is a Gram-positive opportunistic pathogen that has evolved a
complex regulatory network to control virulence. One of the main functions of this …

The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and …

DB Kell, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

Antimicrobial activity of metal and metal‐oxide based nanoparticles

K Gold, B Slay, M Knackstedt… - Advanced …, 2018 - Wiley Online Library
With an increase in antibiotic resistance, a growing interest in developing new antimicrobial
agents has gained popularity. Metal‐and metal‐oxide‐based nanoparticles, surface‐to …

[HTML][HTML] Ferroptotic stress promotes macrophages against intracellular bacteria

R Ma, L Fang, L Chen, X Wang, J Jiang, L Gao - Theranostics, 2022 - ncbi.nlm.nih.gov
Rational: Intracellular bacterial survival is a major factor causing chronic or recurrent
infection, leading to the failure of both host defense and/or antibiotic treatment. However, the …

Nutritional immunity: transition metals at the pathogen–host interface

MI Hood, EP Skaar - Nature Reviews Microbiology, 2012 - nature.com
Transition metals occupy an essential niche in biological systems. Their electrostatic
properties stabilize substrates or reaction intermediates in the active sites of enzymes, and …

Virulence and Fitness Determinants of Uropathogenic Escherichia coli

S Subashchandrabose… - Urinary Tract Infections …, 2017 - Wiley Online Library
Urinary tract infections (UTIs) are one of the most common bacterial infections affecting
humans, and uropathogenic Escherichia coli (UPEC) is the etiological agent in 75% to 95 …

Iron acquisition systems of gram-negative bacterial pathogens define TonB-dependent pathways to novel antibiotics

PE Klebba, SMC Newton, DA Six, A Kumar… - Chemical …, 2021 - ACS Publications
Iron is an indispensable metabolic cofactor in both pro-and eukaryotes, which engenders a
natural competition for the metal between bacterial pathogens and their human or animal …

Molecular mechanisms of Cr (VI) resistance in bacteria and fungi

C Viti, E Marchi, F Decorosi… - FEMS microbiology …, 2014 - academic.oup.com
Abstract Hexavalent chromium [Cr (VI)] contamination is one of the main problems of
environmental protection because the Cr (VI) is a hazard to human health. The Cr (VI) form …

Recent developments in understanding the iron acquisition strategies of gram positive pathogens

JR Sheldon, DE Heinrichs - FEMS microbiology reviews, 2015 - academic.oup.com
Iron is a versatile redox-active catalyst and a required cofactor within a diverse array of
biological processes. To almost all organisms, iron is both essential and potentially toxic …

Elemental economy: microbial strategies for optimizing growth in the face of nutrient limitation

SS Merchant, JD Helmann - Advances in microbial physiology, 2012 - Elsevier
Microorganisms play a dominant role in the biogeochemical cycling of nutrients. They are
rightly praised for their facility for fixing both carbon and nitrogen into organic matter, and …