Hypertension management in frail older adults: a gap in evidence

G Rivasi, V Tortu, MF D'Andria, G Turrin… - Journal of …, 2021 - journals.lww.com
Hypertension management is challenging in frail older adults. The balance between
treatment risks and benefits may be difficult to achieve due to an increased vulnerability to …

Medication management in frail older people: consensus principles for clinical practice, research, and education

SJ Liau, S Lalic, JK Sluggett, M Cesari, G Onder… - Journal of the American …, 2021 - Elsevier
Frailty is a geriatric condition associated with increased vulnerability to adverse drug events
and medication-related harm. Existing clinical practice guidelines rarely provide medication …

An up-to-date article regarding particularities of drug treatment in patients with chronic heart failure

V Buda, A Prelipcean, D Cozma, DE Man… - Journal of clinical …, 2022 - mdpi.com
Since the prevalence of heart failure (HF) increases with age, HF is now one of the most
common reasons for the hospitalization of elderly people. Although the treatment strategies …

Adverse drug reactions and associated patient characteristics in older community-dwelling adults: a 6-year prospective cohort study

AS Doherty, F Boland, F Moriarty, T Fahey… - British Journal of General …, 2023 - bjgp.org
Background To date, research on adverse drug reactions (ADRs) has focused on secondary
care, and there is a paucity of studies that have prospectively examined ADRs affecting …

Drug utilisation review among geriatric patients with noncommunicable diseases in a primary care setting in Malaysia

P Manirajan, P Sivanandy - Healthcare, 2023 - mdpi.com
A prospective cross-sectional study was conducted to analyse the drugs prescribed to the
elderly population with noncommunicable diseases and to determine the polypharmacy at a …

Postural hypotension

A Gilani, SP Juraschek, MJ Belanger, JE Vowles… - bmj, 2021 - bmj.com
• Postural hypotension is a drop in blood pressure (≥ 20 mm Hg systolic and/or≥ 10 mm Hg
diastolic) that occurs within 3 minutes of standing• Test for it in people who have symptoms …

Plasma trough concentrations of antihypertensive drugs for the assessment of treatment adherence: a meta-analysis

EH Groenland, MEAM van Kleef, ML Bots… - …, 2021 - Am Heart Assoc
Biochemical drug screening by liquid chromatography-tandem mass spectrometry in plasma
is an accurate method for the quantification of plasma concentrations of antihypertensive …

Sodium-glucose cotransporter 2 inhibitors in frail patients with heart failure: clinical experience of a heart failure unit

D Villarreal, H Ramírez, V Sierra, JS Amarís… - Drugs & Aging, 2023 - Springer
Objective The objective of this study was to determine the difference in tolerance for sodium
glucose cotransporter 2 inhibitors between patients with heart failure classified as frail …

'Under pressure': The role of therapeutic drug monitoring in the treatment of hypertension

J Versmissen, J van Steenkiste… - British Journal of …, 2024 - Wiley Online Library
Antihypertensive drugs do not qualify as optimal candidates for therapeutic drug monitoring
(TDM), given their obvious physiological effect, the absence of a clear relationship between …

DiffErenCes in AntihypertenSive drug blood levels in patients with HypertensiON (DECISION): protocol for a prospective observational study comparing …

D Hassan, LEJ Peeters, BCP Koch… - High Blood Pressure & …, 2022 - Springer
Adequate controlled blood pressure decreases the risk of cardiovascular events. However,
the elderly are more vulnerable and thereby more prone to side effects of antihypertensive …