Recent Strategies to Overcome Breast Cancer Resistance

MM Khan, SSK Yalamarty, BA Rajmalani… - Critical Reviews in …, 2024 - Elsevier
Breast cancer is potentially a lethal disease and a leading cause of death in women.
Chemotherapy and radiotherapy are the most frequently used treatment options. Drug …

Targeting hypoxia-inducible Factor-1 (HIF-1) in Cancer: emerging therapeutic strategies and pathway regulation

RA Qannita, AI Alalami, AA Harb, SM Aleidi, J Taneera… - Pharmaceuticals, 2024 - mdpi.com
Hypoxia-inducible factor-1 (HIF-1) is a key regulator for balancing oxygen in the cells. It is a
transcription factor that regulates the expression of target genes involved in oxygen …

Oncolytic Virus‐Like Nanoparticles for Tumor‐Specific Gene Delivery

Y Li, H Yang, X Zong, X Li, P Yuan… - Advanced Functional …, 2024 - Wiley Online Library
Nucleic acid drugs are widely used in biomedical fields. However, one of the main
challenges in vivo is to selectively deliver nucleic acid drugs to subcellular compartments …

[HTML][HTML] Function of microRNAs in normal and abnormal ovarian activities: A review focus on microRNA-21

R Arefnezhad, H Roghani-Shahraki… - … Journal of Fertility & …, 2024 - ncbi.nlm.nih.gov
Some failures in ovary function, like folliculogenesis and oogenesis, can give rise to various
infertility-associated problems, including polycystic ovary syndrome (PCOS) and premature …

ROS-Responsive Bola-Lipid Nanoparticles as a Codelivery System for Gene/Photodynamic Combination Therapy

RM Zhao, QF Zhang, XL Tian, JJ Chen… - Molecular …, 2024 - ACS Publications
The nonviral delivery systems that combine genes with photosensitizers for multimodal
tumor gene/photodynamic therapy (PDT) have attracted much attention. In this study, a …

In situ transmission electron microscopy (TEM) study on the structural evolution behavior of nano Sn sheets under a thermal field

X Zhou, J Zhang, H Li, C Ma, Y Zhao… - Journal of Materials …, 2024 - pubs.rsc.org
Sn-based solders have been used widely in chip attachment and surface mount processes
in the electronic packaging industry, where Sn plays an indispensable role as the main …

Revolutionizing cancer therapy using tetrahedral DNA nanostructures as intelligent drug delivery systems

A Sharma, P Vaswani, D Bhatia - Nanoscale Advances, 2024 - pubs.rsc.org
DNA nanostructures have surfaced as intriguing entities with vast potential in biomedicine,
notably in the drug delivery area. Tetrahedral DNA nanostructures (TDNs) have received …

The Current Situation and Development Prospect of Whole-Genome Screening

C Yang, Y Lei, T Ren, M Yao - International Journal of Molecular Sciences, 2024 - mdpi.com
High-throughput genetic screening is useful for discovering critical genes or gene
sequences that trigger specific cell functions and/or phenotypes. Loss-of-function genetic …

Precision arrows: Navigating breast cancer with nanotechnology siRNA

N Jayaswal, S Srivastava, S Kumar, SB Sridhar… - International Journal of …, 2024 - Elsevier
Nanotechnology-based drug delivery systems, including siRNA, present an innovative
approach to treating breast cancer, which disproportionately affects women. These systems …

An innovative gene expression modulating strategy by converting nucleic acids into HNC therapeutics using carrier-free nanoparticles

H Liu, Y Huang, Z Li, S Han, T Liu, Q Zhao - Frontiers in Immunology, 2024 - frontiersin.org
Background Cell fate and microenvironmental changes resulting from aberrant expression
of specific proteins in tumors are one of the major causes of inadequate anti-tumor immune …