The classification of epithelial ovarian cancer has been substantially revised, with an
increased appreciation of the cellular origins and molecular aberrations of the different …

Treatment of ovarian cancer remains challenging despite the high complete response rate
seen after maximal surgical debulking surgery and platinum-combination chemotherapy. as …

Purpose To evaluate the safety and clinical activity of mirvetuximab soravtansine, an
antibody-drug conjugate comprising a humanized anti-folate receptor alpha (FRα) …

Epithelial ovarian cancer is the most lethal gynecological malignancy in the Western world.
A major impediment for the successful treatment is the development of drug resistance. The …

Cisplatin resistance significantly affects the survival rate of patients with ovarian cancer.
However, the main mechanism underlying cisplatin resistance in ovarian cancer remains …

Elevated folate receptor alpha (FRα) expression is characteristic of epithelial ovarian cancer
(EOC), thus establishing this receptor as a candidate target for the development of novel …

Ovarian cancer (OvCa) is the most lethal gynecological malignancy in the United States
primarily due to lack of a reliable early diagnostic, high incidence of chemo-resistant …

Background Drug resistance hampers the efficient treatment of malignancies, including
advanced stage ovarian cancer, which has a 5-year survival rate of only 30%. The molecular …

OBJECTIVE: Ovarian cancer is a gynecological malignancy with high mortality rates all over
the world. Markers for diagnosis, prognosis and therapy are urgently required to improve the …

Aims High‐grade serous carcinoma (HGSC) is the most common tubal/ovarian malignant
tumour, and usually presents at an advanced stage. Interval debulking surgery (IDS) after …