The advent of iPSCs has brought about a significant transformation in stem cell research,
opening up promising avenues for advancing cancer treatment. The formation of cancer is a …

Organoids are established through in vitro 3D culture, and they can mimic the structure and
physiological functions of organs or tissues in vivo. Organoids have attracted much attention …

Current research has demonstrated that extracellular vesicles (EVs) and circulating tumor
cells (CTCs) are very closely related in the process of distant tumor metastasis. Primary …

Extracellular vesicles (EVs), involved in essential physiological and pathological processes
of the organism, have emerged as powerful tools for disease treatment owing to their unique …

Patient‐derived organoids (PDOs) developed ex vivo and in vitro are increasingly used for
therapeutic screening. They provide a more physiologically relevant model for drug …

In recent years, remarkable breakthroughs have been reported on antibody‐drug
conjugates (ADCs), with 15 ADCs successfully entering the market over the past decade …

The design of chimeric antigen receptors (CAR) significantly enhances the antitumor efficacy
of T cells. Although some CAR-T products have been approved by FDA in treating …

The treatment for trastuzumab-resistant breast cancer (BC) remains a challenge in clinical
settings. It was known that CD47 is preferentially upregulated in HER2+ BC cells, which is …

Prostate cancer (PCa) has become a public health concern in elderly men due to an ever‐
increasing number of estimated cases. Unfortunately, the available treatments are …

Pancreatic cancer (PC) is a highly malignant cancer characterized by poor prognosis, high
heterogeneity, and intricate heterocellular system. Selecting an appropriate experimental …