In recent years, the role of mitochondria in pathogenic fungi in terms of azole resistance and
fungal pathogenicity has been a rapidly developing field. In this review, we describe the …

Invasive fungal infections increase mortality and morbidity rates worldwide. The treatment of
these infections is still limited due to the low bioavailability and toxicity, requiring therapeutic …

Neutrophils are required for host resistance against Streptococcus pneumoniae, but their
function declines with age. We previously found that CD73, an enzyme required for …

The human fungal pathogen Cryptococcus neoformans is intrinsically resistant to the
echinocandin antifungal drug caspofungin, which targets the β-1, 3-glucan synthase …

Pathogenic fungi require delicate gene regulation mechanisms to adapt to diverse living
environments and escape host immune systems. Recent advances in sequencing …

Antibody immunity is now known to play a critical role in combating mycotic infections. The
identification of molecules that can elicit an antibody response against fungal pathogens is …

When encountering oxidative stress, organisms selectively upregulate antioxidant genes
and simultaneously suppress the translation of most other proteins. Eukaryotes employ …

Candida albicans, a major human fungal pathogen associated with high mortality and/or
morbidity rates in a wide variety of immunocompromised individuals, undergoes a reversible …

Host-pathogen interactions at the molecular level are the key to fungal pathogenesis. Fungal
pathogens utilize several mechanisms such as adhesion, invasion, phenotype switching …

Cryptococcus neoformans is an invasive human fungal pathogen that causes more than
181,000 deaths each year. Studies have demonstrated that pulmonary C. neoformans …