Mutation profiles of follicular thyroid tumors by targeted sequencing
H Duan, X Liu, X Ren, H Zhang, H Wu, Z Liang - Diagnostic Pathology, 2019 - Springer
Background One of the major challenges remaining in the classification of thyroid tumor is
the determination of whether a nodule is benign or malignant. We aimed to characterize the …
the determination of whether a nodule is benign or malignant. We aimed to characterize the …
TERT promoter mutations in thyroid cancer
M Matsuse, N Mitsutake - Endocrine journal, 2023 - jstage.jst.go.jp
TERT promoter mutations (TERT-p mutations) have been found in many types of cancer and
have emerged to play critical roles in tumor progression. The mutations upregulate TERT …
have emerged to play critical roles in tumor progression. The mutations upregulate TERT …
The predictive value of coexisting BRAFV600E and TERT promoter mutations on poor outcomes and high tumour aggressiveness in papillary thyroid carcinoma: A …
B Chen, Y Shi, Y Xu, J Zhang - Clinical endocrinology, 2021 - Wiley Online Library
BRAFV600E mutation is highly prevalent in patients with papillary thyroid carcinoma (PTC),
and TERT promoter (TERTp) mutation is strongly associated with cancer‐related mortality …
and TERT promoter (TERTp) mutation is strongly associated with cancer‐related mortality …
A six-genotype genetic prognostic model for papillary thyroid cancer
A unique prognostic role of the genetic duet of BRAF V600E and TERT promoter mutations
in papillary thyroid cancer (PTC) has been recently established, but the role of RAS mutation …
in papillary thyroid cancer (PTC) has been recently established, but the role of RAS mutation …
Whole-genome Sequencing of Follicular Thyroid Carcinomas Reveal Recurrent Mutations in MicroRNA Processing Subunit DGCR8
JO Paulsson, N Rafati, S DiLorenzo… - The Journal of …, 2021 - academic.oup.com
Background The genomic and transcriptomic landscape of widely invasive follicular thyroid
carcinomas (wiFTCs) and Hürthle cell carcinoma (HCC) are poorly characterized, and …
carcinomas (wiFTCs) and Hürthle cell carcinoma (HCC) are poorly characterized, and …
Intratumor heterogeneity in hepatocellular carcinoma: challenges and opportunities
SM Kalasekar, CH VanSant-Webb, KJ Evason - Cancers, 2021 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is a deadly form of liver cancer that has
poor patient outcomes and survival. Unlike many other cancers, HCC has not seen the …
poor patient outcomes and survival. Unlike many other cancers, HCC has not seen the …
Thyroid cancers of follicular origin in a genomic light: in-depth overview of common and unique molecular marker candidates
N Pstrąg, K Ziemnicka, H Bluyssen, J Wesoły - Molecular cancer, 2018 - Springer
In recent years, thyroid malignances have become more prevalent, especially among
women. The most common sporadic types of thyroid tumors of follicular origin include …
women. The most common sporadic types of thyroid tumors of follicular origin include …
Immune gene signature delineates a subclass of papillary thyroid cancer with unfavorable clinical outcomes
K Kim, S Jeon, TM Kim, CK Jung - Cancers, 2018 - mdpi.com
Papillary thyroid carcinoma (PTC) represents a heterogeneous disease with diverse clinical
outcomes highlighting a need to identify robust biomarkers with clinical relevance. We …
outcomes highlighting a need to identify robust biomarkers with clinical relevance. We …
PD-L1 and IDO1 are expressed in poorly differentiated thyroid carcinoma
Poorly differentiated thyroid carcinoma (PDTC) is an aggressive form of thyroid cancer that
currently has limited effective treatment options. Immune checkpoint inhibitors (ICIs) have …
currently has limited effective treatment options. Immune checkpoint inhibitors (ICIs) have …
DIAGNOSIS OF ENDOCRINE DISEASE: Usefulness of genetic testing of fine-needle aspirations for diagnosis of thyroid cancer
P Stewardson, M Eszlinger… - European Journal of …, 2022 - academic.oup.com
Objective Genetic testing is increasingly used to diagnose or rule out thyroid cancer in
indeterminate fine-needle aspirations. This review evaluates the usefulness of these …
indeterminate fine-needle aspirations. This review evaluates the usefulness of these …