Outsmarting Pathogens with Antibody Engineering
AN Qerqez, RP Silva, JA Maynard - Annual Review of Chemical …, 2023 - annualreviews.org
There is growing interest in identifying antibodies that protect against infectious diseases,
especially for high-risk individuals and pathogens for which no vaccine is yet available …
especially for high-risk individuals and pathogens for which no vaccine is yet available …
The Structures and Binding Modes of Small-Molecule Inhibitors of Pseudomonas aeruginosa Elastase LasB
V Camberlein, G Jézéquel, J Haupenthal, AKH Hirsch - Antibiotics, 2022 - mdpi.com
Elastase B (LasB) is a zinc metalloprotease and a crucial virulence factor of Pseudomonas
aeruginosa. As the need for new strategies to fight antimicrobial resistance (AMR) constantly …
aeruginosa. As the need for new strategies to fight antimicrobial resistance (AMR) constantly …
The involvement of the T6SS vgrG gene in the pathogenicity of Pseudomonas plecoglossicida
D Yang, L Zhao, Q Li, L Huang, Y Qin… - Journal of Fish …, 2023 - Wiley Online Library
Pseudomonas plecoglossicida, the causative agent of white spot disease of large yellow
croaker, has caused serious economic losses to the aquaculture industry. The type VI …
croaker, has caused serious economic losses to the aquaculture industry. The type VI …
Catalytic antibodies: Design, expression, and their applications in medicine
D Zhao, J Chen, X Hu, S Zhang - Applied Biochemistry and Biotechnology, 2023 - Springer
Catalytic antibodies made it feasible to develop new catalysts, which had previously been
the subject of research. Scientists have discovered natural antibodies that can hydrolyze …
the subject of research. Scientists have discovered natural antibodies that can hydrolyze …
Computational discovery of binding mode of anti-TRBC1 antibody and predicted key amino acids of TRBC1
J Saetang, S Sangkhathat, N Jangphattananont… - Scientific Reports, 2022 - nature.com
Peripheral T-cell lymphoma (PTCL) is a type of non-Hodgkin lymphoma that progresses
aggressively with poor survival rate. CAR T cell targeting T-cell receptor β-chain constant …
aggressively with poor survival rate. CAR T cell targeting T-cell receptor β-chain constant …
Quercetin: a promising virulence inhibitor of Pseudomonas aeruginosa LasB in vitro
Y Ren, R Zhu, X You, D Li, M Guo, B Fei, Y Liu… - Applied Microbiology …, 2024 - Springer
With the inappropriate use of antibiotics, antibiotic resistance has emerged as a major
dilemma for patients infected with Pseudomonas aeruginosa. Elastase B (LasB), a crucial …
dilemma for patients infected with Pseudomonas aeruginosa. Elastase B (LasB), a crucial …
Novel Antimicrobials, Drug Delivery Systems and Antivirulence Targets in the Pipeline—From Bench to Bedside
In a fast-paced medical reality, biosciences and bioengineering have become essential
components in medical research and development. The aim of this paper is to characterize …
components in medical research and development. The aim of this paper is to characterize …
Detection via in vitro amplification of lasR gene associated with virulent attribute of Pseudomonas aeruginosa from acute pulmonary infections
Pseudomonas aeruginosa is the most ubiquitous pulmonary pathogen of human which
causes successfully unscrupulous infections in patients with the suppressed immune system …
causes successfully unscrupulous infections in patients with the suppressed immune system …
[PDF][PDF] Bacterial biofilm interactions with human immune cells
K Lee - 2022 - core.ac.uk
Innate immune cells recognise pathogens via specific receptors able to distinguish
structures unique to microorganisms, deemed pathogen associated molecular patterns …
structures unique to microorganisms, deemed pathogen associated molecular patterns …
Contributions of antibodies binding defined epitopes to protection against B. pertussis and SARS-CoV-2
RP Silva - 2022 - repositories.lib.utexas.edu
While antibodies have the potential to reduce the severity of many infections and prevent
transmission of pathogens, microbes have a corresponding capacity to undermine these …
transmission of pathogens, microbes have a corresponding capacity to undermine these …