Molecular recognition, which is the process of biological macromolecules interacting with
each other or various small molecules with a high specificity and affinity to form a specific …

In the modern era of advanced technologies, rapid and accurate analyses are needed, both
for scientific research and for industrial applications. For this reason, the Surface Plasmon …

SPR is a real-time, label-free measurement of binding kinetics and affinity. Success of SPR
biosensor is evident by the growing number of commercially available instruments. In the …

Localized surface plasmon resonance (LSPR) has emerged as a leader among label-free
biosensing techniques in that it offers sensitive, robust, and facile detection. Traditional …

Motivation Computational approaches for identifying the protein–ligand binding affinity can
greatly facilitate drug discovery and development. At present, many deep learning-based …

The optical properties of various nanostructures have been widely adopted for biological
detection, from DNA sequencing to nano-scale single molecule biological function …

Natural small compounds comprise most cellular molecules and bind proteins as substrates,
products, cofactors, and ligands. However, a large-scale investigation of in vivo protein …

G protein-coupled receptors (GPCRs) are the largest family of transmembrane receptors and
are the target of approximately one-third of all Food and Drug Administration (FDA) …

We present a high-throughput screening Raman spectroscopy (HTS-RS) platform for a rapid
and label-free macromolecular fingerprinting of tens of thousands eukaryotic cells. The …

In recent years, researchers have made significant contributions to the field of Surface
Plasmon Resonance sensors and their potential applications. SPR features include real …