Mechanisms linking neurological disorders with reproductive endocrine dysfunction: insights from epilepsy research

CA Cutia, CA Christian-Hinman - Frontiers in Neuroendocrinology, 2023 - Elsevier
Gonadal hormone actions in the brain can both worsen and alleviate symptoms of
neurological disorders. Although neurological conditions and reproductive endocrine …

The role of endogenous neuroprotective mechanisms in the prevention of retinal ganglion cells degeneration

M Pietrucha-Dutczak, M Amadio, S Govoni… - Frontiers in …, 2018 - frontiersin.org
Retinal neurons are not able to undergo spontaneous regeneration in response to damage.
A variety of stressors, ie, UV radiation, high temperature, ischemia, allergens, and others …

Growth hormone receptor mutations related to individual dwarfism

S Lin, C Li, C Li, X Zhang - International journal of molecular sciences, 2018 - mdpi.com
Growth hormone (GH) promotes body growth by binding with two GH receptors (GHRs) at
the cell surface. GHRs interact with Janus kinase, signal transducers, and transcription …

In silico Analysis of ACE2 Receptor to Find Potential Herbal Drugs in COVID-19 Associated Neurological Dysfunctions

J Hou, AM Bhat, S Ahmad, K Raza… - Natural Product …, 2022 - journals.sagepub.com
COVID-19 mainly causes the collapse of the pulmonary system thereby causing a dearth of
oxygen in the human body. Patients infected with this viral disease have been reported to …

A comparative update on the neuroendocrine regulation of growth hormone in vertebrates

EJ Velez, S Unniappan - Frontiers in Endocrinology, 2021 - frontiersin.org
Growth hormone (GH), mainly produced from the pituitary somatotrophs is a key endocrine
regulator of somatic growth. GH, a pleiotropic hormone, is also involved in regulating vital …

The roles of GnRH in the human central nervous system

N Wickramasuriya, R Hawkins, C Atwood… - Hormones and behavior, 2022 - Elsevier
It is widely known that GnRH plays a role in facilitating reproductive function via the HPG
axis, and this was once believed to be its only function. However, over the last several …

Cognitive and adaptive effects of early growth hormone treatment in Prader–Willi syndrome patients: a cohort study

A Ayet-Roger, L Joga-Elvira, A Caixàs… - Journal of clinical …, 2022 - mdpi.com
Background: Prader–Willi Syndrome (PWS) is a genetically based neurodevelopmental
disease characterized by obesity, hyperphagia, and mild to moderate intellectual disability …

Growth hormone (GH) enhances endogenous mechanisms of neuroprotection and neuroplasticity after oxygen and glucose deprivation injury (OGD) and …

JD Olivares-Hernández, JE Balderas-Márquez… - Neural …, 2021 - Wiley Online Library
As a classical growth promoter and metabolic regulator, growth hormone (GH) is involved in
development of the central nervous system (CNS). This hormone might also act as a …

Metabolic hormones are integral regulators of female reproductive health and function

F Athar, M Karmani, NM Templeman - Bioscience Reports, 2024 - portlandpress.com
The female reproductive system is strongly influenced by nutrition and energy balance. It is
well known that food restriction or energy depletion can induce suppression of reproductive …

Translational challenges in advancing regenerative therapy for treating neurological disorders using nanotechnology

CL Nemeth, AS Fine, A Fatemi - Advanced Drug Delivery Reviews, 2019 - Elsevier
The focus of regenerative therapies is to replace or enrich diseased or injured cells and
tissue in an attempt to replenish the local environment and function, while slowing or halting …