Ellagitannins, promising pharmacological agents for the treatment of cancer stem cells
Z Senobari, G Karimi… - Phytotherapy Research, 2022 - Wiley Online Library
Human tumors comprise subpopulations of cells called cancer stem cells (CSCs) that
possess stemness properties. CSCs can initiate tumors and cause recurrence, metastasis …
possess stemness properties. CSCs can initiate tumors and cause recurrence, metastasis …
The pharmacological use of ellagic acid-rich pomegranate fruit
In recent years, the therapeutic use of non-drug substances such as herbal and medicinal
foods is increasing progressively. Of these substances, Punica granatum L., which is an …
foods is increasing progressively. Of these substances, Punica granatum L., which is an …
In-silico ADMET profile of Ellagic Acid from Syzygium cumini: A Natural Biaryl Polyphenol with Therapeutic Potential to Overcome Diabetic Associated Vascular …
S Ramya, M Murugan, K Krishnaveni… - Journal of Drug …, 2022 - jddtonline.info
Abstract Plant Based Natural Products (PBNPs) are the primary source of natural
antioxidants capable of neutralizing or eliminating harmful Reactive Oxygen Species (ROS) …
antioxidants capable of neutralizing or eliminating harmful Reactive Oxygen Species (ROS) …
Central and peripheral antinociceptive effects of ellagic acid in different animal models of pain
MT Mansouri, B Naghizadeh, B Ghorbanzadeh… - European journal of …, 2013 - Elsevier
The present study was conducted to evaluate the analgesic effects of po, ip, or icv
administration of ellagic acid (EA), and investigate the possible mechanisms underlying the …
administration of ellagic acid (EA), and investigate the possible mechanisms underlying the …
Ellagic acid inhibits proliferation and induced apoptosis via the Akt signaling pathway in HCT-15 colon adenocarcinoma cells
S Umesalma, P Nagendraprabhu… - Molecular and cellular …, 2015 - Springer
Chemoprevention is regarded as one of the most promising and realistic approaches in the
prevention of human cancer. Ellagic acid (EA) has been known for its chemopreventive …
prevention of human cancer. Ellagic acid (EA) has been known for its chemopreventive …
Ellagic acid attenuates testicular disruption in rheumatoid arthritis via targeting inflammatory signals, oxidative perturbations and apoptosis
Background and purpose Reduced male fertility has been regarded as a serious
complication of rheumatoid arthritis. Phytochemicals have been described as protective …
complication of rheumatoid arthritis. Phytochemicals have been described as protective …
The modulatory effect of ellagic acid and rosmarinic acid on ultraviolet‐B‐induced cytokine/chemokine gene expression in skin keratinocyte (HaCaT) cells
S Lembo, A Balato, R Di Caprio, T Cirillo… - BioMed Research …, 2014 - Wiley Online Library
Ultraviolet radiation (UV) induces an increase in multiple cutaneous inflammatory mediators.
Ellagic acid (EA) and rosmarinic acid (RA) are natural anti‐inflammatory and …
Ellagic acid (EA) and rosmarinic acid (RA) are natural anti‐inflammatory and …
[HTML][HTML] Antitumor activity of 5-fluorouracil polymeric nanogel synthesized by gamma radiation on a rat model of colon carcinoma: a proposed mechanism
OAR Abo-Zaid, FSM Moawed, WEM Barakat… - Discover Oncology, 2023 - Springer
Abstract The use of 5-fluorouracil (5-FU) is associated with multifaceted challenges and poor
pharmacokinetics. Accordingly, our study was designed to prepare 5-FU nanogel as a new …
pharmacokinetics. Accordingly, our study was designed to prepare 5-FU nanogel as a new …
Quercetin attenuates TNF-induced inflammation in hepatic cells by inhibiting the NF-κB pathway
AB Granado-Serrano, MÁ Martín, L Bravo… - Nutrition and …, 2012 - Taylor & Francis
The dietary flavonoid quercetin is an antioxidant that possesses antiinflammatory and
anticarcinogenic properties and may modulate signaling pathways. Inflammation is …
anticarcinogenic properties and may modulate signaling pathways. Inflammation is …
Neuroprotective effects of ellagic acid on cuprizone-induced acute demyelination through limitation of microgliosis, adjustment of CXCL12/IL-17/IL-11 axis and …
N Sanadgol, F Golab, Z Tashakkor, N Taki… - Pharmaceutical …, 2017 - Taylor & Francis
Context: Ellagic acid (EA) is a natural phenol antioxidant with various therapeutic activities.
However, the efficacy of EA has not been examined in neuropathologic conditions …
However, the efficacy of EA has not been examined in neuropathologic conditions …