[HTML][HTML] In vitro and in vivo anticancer studies of 2'-hydroxy chalcone derivatives exhibit apoptosis in colon cancer cells by HDAC inhibition and cell cycle arrest
AN Pande, S Biswas, ND Reddy, BS Jayashree… - EXCLI …, 2017 - ncbi.nlm.nih.gov
Considering the therapeutic values of bioflavonoids in colon cancer treatment, six 2ʹ-
hydroxy chalcones (C1-C6) were synthesized, characterized and screened for in vitro …
hydroxy chalcones (C1-C6) were synthesized, characterized and screened for in vitro …
[HTML][HTML] Lagerstroemia Speciosa (L.) Pers Leaf Extract Attenuates Lung Tumorigenesis via Alleviating Oxidative Stress, Inflammation and Apoptosis
AM Mousa, NM El-Sammad, AH Abdel-Halim, N Anwar… - Biomolecules, 2019 - mdpi.com
One of the major etiological factors that account for lung cancer is tobacco use. Benzo (a)
pyrene [B (a) P], one of the main constituents of tobacco smoke, has a key role in lung …
pyrene [B (a) P], one of the main constituents of tobacco smoke, has a key role in lung …
[HTML][HTML] Effect of ellagic acid on fermentation quality and bacterial community of stylo silage
X Zou, D Chen, H Lv, Q Zhang, P Zheng - Fermentation, 2021 - mdpi.com
This study was conducted to investigate the effect of ellagic acid on the bacterial community
and fermentability of stylo silage. Three treatments of stylo silage were used: control (CK) …
and fermentability of stylo silage. Three treatments of stylo silage were used: control (CK) …
1-Methylnicotinamide attenuates lipopolysaccharide-induced cognitive deficits via targeting neuroinflammation and neuronal apoptosis
R Mu, Y Tan, L Fu, MN Islam, M Hu, H Hong… - International …, 2019 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disease that affects cognition and
behavior. The neuroinflammatory response in the brain is an important pathological …
behavior. The neuroinflammatory response in the brain is an important pathological …
Luteolin supplementation adjacent to aspirin treatment reduced dimethylhydrazine-induced experimental colon carcinogenesis in rats
NHA Osman, UZ Said, AM El-Waseef, ESA Ahmed - Tumor Biology, 2015 - Springer
Previous studies have shown that aspirin is used in colon cancer treatment. However, long-
term of Aspirin usage is limited to gastric and renal toxicity. Luteolin (LUT) has cancer …
term of Aspirin usage is limited to gastric and renal toxicity. Luteolin (LUT) has cancer …
Involvement of L-arginine/NO/cGMP/KATP channel pathway in the peripheral antinociceptive actions of ellagic acid in the rat formalin test
The present study was conducted to evaluate the local antinociceptive actions of EA and the
possible involvement of l-arginine/NO/cGMP/K ATP channel pathway in this effect using …
possible involvement of l-arginine/NO/cGMP/K ATP channel pathway in this effect using …
[HTML][HTML] Therapeutic effects of ellagic acid on memory, hippocampus electrophysiology deficits, and elevated TNF-α level in brain due to experimental traumatic brain …
Objective (s): Cognitive defects such as learning and memory impairment are amongst the
most repetitious sequelae after sever and moderate traumatic brain injury (TBI). It was …
most repetitious sequelae after sever and moderate traumatic brain injury (TBI). It was …
Punicalagin and ellagic acid containing Punica granatum L. fruit rind extract prevents vincristine-induced neuropathic pain in rats: an in silico and in vivo evidence of …
Objectives: We aimed to investigate the protective potential of Punica granatum L. fruit rind
extract (PFE) containing punicalagin (10.3% W/W), ellagic acid (EA)(2.7% W/W) in …
extract (PFE) containing punicalagin (10.3% W/W), ellagic acid (EA)(2.7% W/W) in …
Epigenetic modulation of mechanisms involved in inflammation: influence of selected polyphenolic substances on histone acetylation state
In the present study, we have investigated the influence of low concentrations of
polyphenols (5μM) on histone acetyltransferase (HAT) and histone deacetylase (HDAC) …
polyphenols (5μM) on histone acetyltransferase (HAT) and histone deacetylase (HDAC) …
[HTML][HTML] The pro-oxidant, apoptotic and anti-angiogenic effects of selenium supplementation on colorectal tumors induced by 1, 2-dimethylhydrazine in BALB/C mice
MS Ali, RM Hussein, MA Kandeil - Reports of Biochemistry & …, 2019 - ncbi.nlm.nih.gov
Background: Selenium is a mineral that showed both pro-and anti-oxidant activities in
various disease models. In this study, we evaluated the anti-tumor effect of selenium against …
various disease models. In this study, we evaluated the anti-tumor effect of selenium against …