Mesenchymal stromal cells and their secretome: new therapeutic perspectives for skeletal muscle regeneration

M Sandonà, L Di Pietro, F Esposito… - … in bioengineering and …, 2021 - frontiersin.org
Mesenchymal stromal cells (MSCs) are multipotent cells found in different tissues: bone
marrow, peripheral blood, adipose tissues, skeletal muscle, perinatal tissues, and dental …

Recent advances of exosomes in soft tissue injuries in sports medicine: A critical review on biological and biomaterial applications

Y Xue, N Riva, L Zhao, J Shieh, YT Chin, A Gatt… - Journal of Controlled …, 2023 - Elsevier
Sports medicine is generally associated with soft tissue injuries including muscle injuries,
meniscus and ligament injuries, tendon ruptures, tendinopathy, rotator cuff tears, and tendon …

[HTML][HTML] Engineering homologous platelet-rich plasma, platelet-rich plasma-derived exosomes, and mesenchymal stem cell-derived exosomes-based dual …

BM Bakadia, AAQ Ahmed, L Lamboni, Z Shi… - Bioactive Materials, 2023 - Elsevier
The management of diabetic wounds remains a critical therapeutic challenge. Platelet-rich
plasma (PRP) gel, PRP-derived exosomes (PRP-Exos), and mesenchymal stem cell-derived …

Bone-targeting delivery of platelet lysate exosomes ameliorates glucocorticoid-induced osteoporosis by enhancing bone-vessel coupling

G Zheng, HW Ma, GH Xiang, GL He, HC Cai… - Journal of …, 2022 - Springer
Abstract Background Glucocorticoids (GCs) overuse is associated with decreased bone
mass and osseous vasculature destruction, leading to severe osteoporosis. Platelet lysates …

Adipose-derived stem cells (ADSCs) and platelet-rich plasma (PRP) loaded gelatin/silk fibroin hydrogels for improving healing in a murine pressure ulcer model

K Lu, K Li, M Zhang, Z Fang, P Wu, L Feng… - Chemical Engineering …, 2021 - Elsevier
Pressure ulcers are areas of localized damage to the skin and underlying tissue, which
impose a major burden to patients and medical systems. Natural polymeric hydrogels …

Sphingosine-1-phosphate derived from PRP-Exos promotes angiogenesis in diabetic wound healing via the S1PR1/AKT/FN1 signalling pathway

T Chen, P Song, M He, S Rui, X Duan, Y Ma… - Burns & …, 2023 - academic.oup.com
Abstract Background Sphingosine-1-phosphate (S1P), a key regulator of vascular
homeostasis and angiogenesis, is enriched in exosomes derived from platelet-rich plasma …

Infrapatellar fat pad mesenchymal stromal cell–derived exosomes accelerate tendon-bone healing and intra-articular graft remodeling after anterior cruciate ligament …

J Xu, Z Ye, K Han, T Zheng, T Zhang… - … American journal of …, 2022 - journals.sagepub.com
Background: Exosomes derived from mesenchymal stromal cells (MSCs) reportedly
enhance the healing process. However, no studies have investigated the effect of exosomes …

Platelet-derived extracellular vesicles for regenerative medicine

M Antich-Rosselló, MA Forteza-Genestra… - International journal of …, 2021 - mdpi.com
Extracellular vesicles (EVs) present a great potential for the development of new treatments
in the biomedical field. To be used as therapeutics, many different sources have been used …

Advances in platelet rich plasma-derived extracellular vesicles for regenerative medicine: A systematic-narrative review

E Anitua, M Troya, JM Falcon-Pérez… - International Journal of …, 2023 - mdpi.com
The use of platelet-rich plasma (PRP) has gained increasing interest in recent decades. The
platelet secretome contains a multitude of growth factors, cytokines, chemokines, and other …

[HTML][HTML] Exosomes: Potential key players towards novel therapeutic options in diabetic wounds

J Feng, Y Yao, Q Wang, X Han, X Deng, Y Cao… - Biomedicine & …, 2023 - Elsevier
Diabetic wounds are usually difficult to heal, and wounds in foot in particular are often
aggravated by infection, trauma, diabetic neuropathy, peripheral vascular disease and other …