Translation of pre-clinical studies into successful clinical trials for Alzheimer's disease: what are the roadblocks and how can they be overcome?

A Banik, RE Brown, J Bamburg… - Journal of …, 2015 - content.iospress.com
Preclinical studies are essential for translation to disease treatments and effective use in
clinical practice. An undue emphasis on single approaches to Alzheimer's disease (AD) …

What is atypia? Use, misuse and overuse of the term atypia in diagnostic cytopathology

SE Pambuccian - Journal of the American Society of Cytopathology, 2015 - Elsevier
The term “atypical” was introduced by the founder of modern cytodiagnosis, Dr. George N.
Papanicolaou, to convey a very low suspicion of (pre) malignancy. Despite controversies …

[HTML][HTML] Bestcyte® cell sorter imaging system: Primary and adjudicative whole slide image rescreening review times of 500 thinprep pap test thin-layers-an intra …

N Chantziantoniou - Journal of pathology informatics, 2022 - Elsevier
Abstract Background The novel Artificial Intelligence-driven BestCyte® Cell Sorter Imaging
System (BestCyte) enables hybrid digital screening through classification and sorting of tiles …

A practical approach to squamous abnormalities on cervical cytology: Overview of interpretive criteria and guidance for altering thresholds in response to quality …

MJ Thrall - Acta Cytologica, 2023 - karger.com
Background: Squamous intraepithelial lesions observed in Papanicolaou (Pap) test
gynecologic cytology arise as a result of infection of the cervicovaginal tract by human …

[HTML][HTML] BestCyte® primary screening of 500 ThinPrep Pap Test thin-layers: 3 Cytologists' Interobserver diagnostic concordance with predicate manual microscopy …

N Chantziantoniou - Journal of pathology informatics, 2023 - Elsevier
Abstract Background The BestCyte® Cell Sorter Imaging System (BestCyte) facilitates
algorithmic discrimination of clinically relevant cells in Pap test cytopathology by classifying …

NILM Pap slides from women 30 years of age and older with positive high-risk HPV DNA: focused rescreening prior to report issuance, an enhanced quality control …

K Cormier, M Schaaf, S Hamilton… - American Journal of …, 2014 - academic.oup.com
Abstract Objectives: Clinical Laboratory Improvement Amendments of 1988 (CLIA'88)
regulations specify that at least 10% of negative Papanicolaou (Pap) slides be rescreened …

Correlation of cervical cytology with high‐risk HPV molecular diagnosis, genotypes, and histopathology—a four year study from the UAE

K Krishnan, A Thomas - Diagnostic Cytopathology, 2016 - Wiley Online Library
Background Cervical cancer is one of the most common cancers among women in the world
and in the Middle East. Its prevention and screening strategies assume great importance …

[HTML][HTML] Current cytology practices in Korea: a nationwide survey by the Korean Society for Cytopathology

EJ Oh, CK Jung, DH Kim, HK Kim… - … of Pathology and …, 2017 - synapse.koreamed.org
Background Limited data are available on the current status of cytology practices in Korea.
This nationwide study presents Korean cytology statistics from 2015. Methods A nationwide …

Quality metrics in non-gynecologic cytology: results from the 2022 American Society of Cytopathology survey

VF Torous, CJ VandenBussche, ML Randolph… - Journal of the American …, 2023 - Elsevier
Introduction Rapid advancements in minimally invasive techniques and the discovery of
molecular biomarkers have resulted in major changes in the practice of non-gynecologic …

Atypical squamous cells

FW Abdul-Karim, CN Powers, JS Berek… - The Bethesda System …, 2015 - Springer
The TBS category of “atypical squamous cells (ASC)” derives from the concept that a
significant number of cases show changes that, while abnormal, are morphologically …