Harnessing natural killer cells for cancer immunotherapy: dispatching the first responders
NA Maskalenko, D Zhigarev… - Nature reviews Drug …, 2022 - nature.com
Natural killer (NK) cells have crucial roles in the innate immunosurveillance of cancer and
viral infections. They are 'first responders' that can spontaneously recognize abnormal cells …
viral infections. They are 'first responders' that can spontaneously recognize abnormal cells …
NK cells for cancer immunotherapy
N Shimasaki, A Jain, D Campana - Nature reviews Drug discovery, 2020 - nature.com
Natural killer (NK) cells can swiftly kill multiple adjacent cells if these show surface markers
associated with oncogenic transformation. This property, which is unique among immune …
associated with oncogenic transformation. This property, which is unique among immune …
Natural killer cells: development, maturation, and clinical utilization
AM Abel, C Yang, MS Thakar… - Frontiers in …, 2018 - frontiersin.org
Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-
tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells …
tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells …
The X-linked epigenetic regulator UTX controls NK cell-intrinsic sex differences
MI Cheng, JH Li, L Riggan, B Chen, RY Tafti… - Nature …, 2023 - nature.com
Viral infection outcomes are sex biased, with males generally more susceptible than
females. Paradoxically, the numbers of antiviral natural killer (NK) cells are increased in …
females. Paradoxically, the numbers of antiviral natural killer (NK) cells are increased in …
Natural killer cells: from innate to adaptive features
AM Mujal, RB Delconte, JC Sun - Annual review of immunology, 2021 - annualreviews.org
Natural killer (NK) cells are innate lymphocytes that provide critical host defense against
pathogens and cancer. Originally heralded for their early and rapid effector activity, NK cells …
pathogens and cancer. Originally heralded for their early and rapid effector activity, NK cells …
NK cells and cancer: you can teach innate cells new tricks
Natural killer (NK) cells are the prototype innate lymphoid cells endowed with potent cytolytic
function that provide host defence against microbial infection and tumours. Here, we review …
function that provide host defence against microbial infection and tumours. Here, we review …
Dental ceramics: a review of new materials and processing methods
LH Silva, E LIMA, RBP Miranda, SS Favero… - Brazilian oral …, 2017 - SciELO Brasil
The evolution of computerized systems for the production of dental restorations associated
to the development of novel microstructures for ceramic materials has caused an important …
to the development of novel microstructures for ceramic materials has caused an important …
Immune suppression in gliomas
Introduction The overall survival in patients with gliomas has not significantly increased in
the modern era, despite advances such as immunotherapy. This is in part due to their …
the modern era, despite advances such as immunotherapy. This is in part due to their …
The 3 major types of innate and adaptive cell-mediated effector immunity
F Annunziato, C Romagnani, S Romagnani - Journal of Allergy and Clinical …, 2015 - Elsevier
The immune system has tailored its effector functions to optimally respond to distinct species
of microbes. Based on emerging knowledge on the different effector T-cell and innate …
of microbes. Based on emerging knowledge on the different effector T-cell and innate …
Cytotoxicity of metal‐based nanoparticles: from mechanisms and methods of evaluation to pathological manifestations
P Xiong, X Huang, N Ye, Q Lu, G Zhang… - Advanced …, 2022 - Wiley Online Library
Metal‐based nanoparticles (NPs) are particularly important tools in tissue engineering‐,
drug carrier‐, interventional therapy‐, and biobased technologies. However, their complex …
drug carrier‐, interventional therapy‐, and biobased technologies. However, their complex …