Harnessing natural killer cells for cancer immunotherapy: dispatching the first responders

NA Maskalenko, D Zhigarev… - Nature reviews Drug …, 2022 - nature.com
Natural killer (NK) cells have crucial roles in the innate immunosurveillance of cancer and
viral infections. They are 'first responders' that can spontaneously recognize abnormal cells …

NK cells for cancer immunotherapy

N Shimasaki, A Jain, D Campana - Nature reviews Drug discovery, 2020 - nature.com
Natural killer (NK) cells can swiftly kill multiple adjacent cells if these show surface markers
associated with oncogenic transformation. This property, which is unique among immune …

Natural killer cells: development, maturation, and clinical utilization

AM Abel, C Yang, MS Thakar… - Frontiers in …, 2018 - frontiersin.org
Natural killer (NK) cells are the predominant innate lymphocyte subsets that mediate anti-
tumor and anti-viral responses, and therefore possess promising clinical utilization. NK cells …

The X-linked epigenetic regulator UTX controls NK cell-intrinsic sex differences

MI Cheng, JH Li, L Riggan, B Chen, RY Tafti… - Nature …, 2023 - nature.com
Viral infection outcomes are sex biased, with males generally more susceptible than
females. Paradoxically, the numbers of antiviral natural killer (NK) cells are increased in …

Natural killer cells: from innate to adaptive features

AM Mujal, RB Delconte, JC Sun - Annual review of immunology, 2021 - annualreviews.org
Natural killer (NK) cells are innate lymphocytes that provide critical host defense against
pathogens and cancer. Originally heralded for their early and rapid effector activity, NK cells …

NK cells and cancer: you can teach innate cells new tricks

MG Morvan, LL Lanier - Nature Reviews Cancer, 2016 - nature.com
Natural killer (NK) cells are the prototype innate lymphoid cells endowed with potent cytolytic
function that provide host defence against microbial infection and tumours. Here, we review …

Dental ceramics: a review of new materials and processing methods

LH Silva, E LIMA, RBP Miranda, SS Favero… - Brazilian oral …, 2017 - SciELO Brasil
The evolution of computerized systems for the production of dental restorations associated
to the development of novel microstructures for ceramic materials has caused an important …

Immune suppression in gliomas

MM Grabowski, EW Sankey, KJ Ryan… - Journal of neuro …, 2021 - Springer
Introduction The overall survival in patients with gliomas has not significantly increased in
the modern era, despite advances such as immunotherapy. This is in part due to their …

The 3 major types of innate and adaptive cell-mediated effector immunity

F Annunziato, C Romagnani, S Romagnani - Journal of Allergy and Clinical …, 2015 - Elsevier
The immune system has tailored its effector functions to optimally respond to distinct species
of microbes. Based on emerging knowledge on the different effector T-cell and innate …

Cytotoxicity of metal‐based nanoparticles: from mechanisms and methods of evaluation to pathological manifestations

P Xiong, X Huang, N Ye, Q Lu, G Zhang… - Advanced …, 2022 - Wiley Online Library
Metal‐based nanoparticles (NPs) are particularly important tools in tissue engineering‐,
drug carrier‐, interventional therapy‐, and biobased technologies. However, their complex …