Integration of GC–MS and LC–MS for untargeted metabolomics profiling
Recently, metabolomics analyses have become increasingly common in the general
scientific community as it is applied in several researches relating to diseases diagnosis …
scientific community as it is applied in several researches relating to diseases diagnosis …
[HTML][HTML] Human metabolomics: strategies to understand biology
R Ramautar, R Berger, J van der Greef… - Current opinion in …, 2013 - Elsevier
Highlights•Metabolomics provides a functional read-out of the physiological status of an
organism.•A precise (dynamic) description of the clinical phenotype is missing for complex …
organism.•A precise (dynamic) description of the clinical phenotype is missing for complex …
Impact of anesthesia and euthanasia on metabolomics of mammalian tissues: studies in a C57BL/6J mouse model
KA Overmyer, C Thonusin, NR Qi, CF Burant… - PloS one, 2015 - journals.plos.org
A critical application of metabolomics is the evaluation of tissues, which are often the primary
sites of metabolic dysregulation in disease. Laboratory rodents have been widely used for …
sites of metabolic dysregulation in disease. Laboratory rodents have been widely used for …
Canine metabolomics advances
G Carlos, FP Dos Santos, PE Fröehlich - Metabolomics, 2020 - Springer
Introduction Canis lupus familiaris is a domestic dog and many owners consider their pets
as a family member. Medical bills with dogs are overcame only by the health care received …
as a family member. Medical bills with dogs are overcame only by the health care received …
A comparative evaluation of tools to predict metabolite profiles from microbiome sequencing data
Metabolomic analyses of human gut microbiome samples can unveil the metabolic potential
of host tissues and the numerous microorganisms they support, concurrently. As such …
of host tissues and the numerous microorganisms they support, concurrently. As such …
Technical challenges in mass spectrometry-based metabolomics
F Matsuda - Mass spectrometry, 2016 - jstage.jst.go.jp
Metabolomics is a strategy for analysis, and quantification of the complete collection of
metabolites present in biological samples. Metabolomics is an emerging area of scientific …
metabolites present in biological samples. Metabolomics is an emerging area of scientific …
Retention index prediction using quantitative structure–retention relationships for improving structure identification in nontargeted metabolomics
Structure identification in nontargeted metabolomics based on liquid-chromatography
coupled to mass spectrometry (LC-MS) remains a significant challenge. Quantitative …
coupled to mass spectrometry (LC-MS) remains a significant challenge. Quantitative …
Getting the right answers: understanding metabolomics challenges
S Beisken, M Eiden, RM Salek - Expert review of molecular …, 2015 - Taylor & Francis
Small molecules within biological systems provide powerful insights into the biological roles,
processes and states of organisms. Metabolomics is the study of the concentrations …
processes and states of organisms. Metabolomics is the study of the concentrations …
SWATH data independent acquisition mass spectrometry for screening of xenobiotics in biological fluids: Opportunities and challenges for data processing
SWATH data independent acquisition (DIA) mass spectrometry (MS) has become an
established technique in MS-based 'omics' research and is increasingly used for the …
established technique in MS-based 'omics' research and is increasingly used for the …
Amino acids in a targeted versus a non-targeted metabolomics LC-MS/MS assay. Are the results consistent?
J Klepacki, J Klawitter, J Klawitter, A Karimpour-Fard… - Clinical …, 2016 - Elsevier
Background The results of plasma amino acid patterns in samples from kidney transplant
patients with good and impaired renal function using a targeted LC-MS/MS amino acid …
patients with good and impaired renal function using a targeted LC-MS/MS amino acid …