In the 1990s, the identification of a non-selective ion channel, especially responsive to
capsaicin, revolutionized the studies of somatosensation and pain that were to follow. The …

Appropriate regulation of the inflammatory response is essential for survival. Interleukin-10
(IL-10), a well-known anti-inflammatory cytokine, plays a major role in controlling …

Cancer patients often experience changes in mental health, prompting an exploration into
whether nerves infiltrating tumors contribute to these alterations by impacting brain …

Simple Summary Medical control of cancer pain is often unsatisfactory. Narcotic drugs
(opioids) are effective pain killers, but they have important negative effects on the central …

Chronic pain treatment remains a major challenge and pharmacological interventions are
associated with important side effects. Manual medicine treatments such as massage …

Pain is closely associated with the immune system, which exhibits sexual dimorphism. For
these reasons, neuro-immune interactions are suggested to drive sex differences in pain …