The role of exosomes and their applications in cancer

Y Zhou, Y Zhang, H Gong, S Luo, Y Cui - International journal of …, 2021 - mdpi.com
Exosomes are very small extracellular vesicles secreted by multiple cell types and are
extensively distributed in various biological fluids. Recent research indicated that exosomes …

Insight into extracellular vesicle-cell communication: from cell recognition to intracellular fate

L Ginini, S Billan, E Fridman, Z Gil - Cells, 2022 - mdpi.com
Extracellular vesicles (EVs) are heterogamous lipid bilayer-enclosed membranous
structures secreted by cells. They are comprised of apoptotic bodies, microvesicles, and …

[HTML][HTML] New advances in exosome-based targeted drug delivery systems

D Ferreira, JN Moreira, LR Rodrigues - Critical Reviews in Oncology …, 2022 - Elsevier
In recent years, various drug nano-delivery platforms have emerged to enhance drug
effectiveness in cancer treatment. However, their successful translation to clinics have been …

Mesenchymal stem cell-derived extracellular vesicles prevent the development of osteoarthritis via the circHIPK3/miR-124-3p/MYH9 axis

S Li, J Liu, S Liu, W Jiao, X Wang - Journal of nanobiotechnology, 2021 - Springer
Abstract Background Extracellular vesicles (EVs) secreted by mesenchymal stem cells
(MSCs) may play a vital role in a variety of biological processes, including cartilage …

Exosomal long noncoding RNA HOXD-AS1 promotes prostate cancer metastasis via miR-361-5p/FOXM1 axis

Y Jiang, H Zhao, Y Chen, K Li, T Li, J Chen… - Cell death & …, 2021 - nature.com
Abstract Development of distant metastasis is the main cause of deaths in prostate cancer
(PCa) patients. Understanding the mechanism of PCa metastasis is of utmost importance to …

Exosomal miR-338-3p suppresses non-small-cell lung cancer cells metastasis by inhibiting CHL1 through the MAPK signaling pathway

W Tian, X Yang, H Yang, M Lv, X Sun, B Zhou - Cell Death & Disease, 2021 - nature.com
Globally, lung cancer remains one of the most prevalent malignant cancers. However,
molecular mechanisms and functions involved in its pathogenesis have not been clearly …

Extracellular vesicles in triple–negative breast cancer: Immune regulation, biomarkers, and immunotherapeutic potential

K Das, S Paul, A Ghosh, S Gupta, T Mukherjee… - Cancers, 2023 - mdpi.com
Simple Summary Triple–negative breast cancer (TNBC), an aggressive phenotype, is
commonly attributed to the loss of estrogen receptor, progesterone receptor, and human …

Exosomics in oral cancer diagnosis, prognosis, and therapeutics–An emergent and imperative non-invasive natural nanoparticle-based approach

A Bano, R Vats, P Yadav, R Bhardwaj - Critical Reviews in Oncology …, 2022 - Elsevier
Exosomes-the natural nanoparticles belonging to heterogeneous vesicles are released via
nearly all sorts of cells, including tumour cells, to oprate intercellular communication …

Nanoparticle-based approaches for treatment of hematological malignancies: a comprehensive review

U Hani, BHJ Gowda, N Haider, K Ramesh, K Paul… - AAPS …, 2023 - Springer
Blood cancer, also known as hematological malignancy, is one of the devastating types of
cancer that has significantly paved its mortality mark globally. It persists as an extremely …

STAM transports STING oligomers into extracellular vesicles, down‐regulating the innate immune response

J Liang, H Yin - Journal of Extracellular Vesicles, 2023 - Wiley Online Library
Stimulator of interferon genes (STING) mediates the innate immune response against
damaged endogenous double‐strand DNA and exogenous virus infection. The location of …