Membranous nephropathy (MN) is characterized histomorphologically by the presence of
immune deposits in the subepithelial space of the glomerular filtration barrier; its clinical …

Membranous nephropathy (MN) is the major cause of nephrotic syndrome with special
pathological features, caused by the formation of immune complexes in the space between …

Background Circulating serum autoantibodies against the M-type phospholipase A2
receptor (PLA2R-AB) are a key biomarker in the diagnosis and monitoring of primary …

Over the past decade, genome-wide association studies (GWAS) have emerged as a
powerful tool to understand the genetic basis of complex traits in humans. The GWAS …

Membranous nephropathy (MN) is an autoimmune disease caused by binding of circulating
antibodies to podocyte antigens in the kidney. For decades and still today primary MN has …

Recurrence of primary membranous nephropathy after transplantation occurs in up to 44%
of patients and is driven by PLA2R antibody. Here, we asked whether genetic determinants …

904-913. 2. Pakozdi A, Pyne D, Sheaff M, Rajakariar R. Utility of a repeat renal biopsy in
lupus nephritis: a single centre experience. Nephrol Dial Transplant. 2018; 33: 507-513. 3 …

Downstream mechanisms that lead to podocyte injury following phospholipase A2 receptor
(PLA2R) autoimmunity remain elusive. To help define this we compared urinary …

Background: Primary membranous nephropathy (pMN) is the most common cause of
nephrotic syndrome in adults. The discovery of the 2 autoantigens, M-type phospholipase …

Introduction: Membranous nephropathy (MN) is the most common cause of a nephrotic
syndrome in Caucasian adults. The identification of target antigens in MN in the last decade …