Do we AGREE on the targets of antihypertensive drug treatment in older adults: a systematic review of guidelines on primary prevention of cardiovascular diseases

JMK Bogaerts, LM von Ballmoos… - Age and …, 2022 - academic.oup.com
Background translation of the available evidence concerning primary cardiovascular
prevention into clinical guidance for the heterogeneous population of older adults is …

New insights in diagnostics and therapies in syncope: a novel approach to non-cardiac syncope

M Brignole, G Rivasi - Heart, 2021 - heart.bmj.com
This article aims to give advice on how to identify and manage patients with syncope who
are at risk of severe outcomes, that is, at risk of trauma, potentially life-threatening episodes …

Risks associated with intensive blood pressure control in older patients

G Rivasi, L Ceolin, M Capacci… - Polish Heart …, 2023 - journals.viamedica.pl
Hypertension management forms a cornerstone of cardiovascular prevention. Strong
evidence is available supporting the benefits of blood pressure (BP) lowering in older adults …

The association of uric acid with mortality modifies at old age: data from the uric acid right for heart health (URRAH) study

A Ungar, G Rivasi, M Di Bari, A Virdis… - Journal of …, 2022 - journals.lww.com
Objectives: In older individuals, the role of serum uric acid (SUA) as risk factor for mortality is
debated. This study investigated the association of SUA with all-cause and cardiovascular …

Hypertension treatment in frail older adults: a systematic review and appraisal of guidelines

K Hu, G Zhou, M Jiang, X Wei, J Yu, L Liu, Z Wang… - Drugs & Aging, 2023 - Springer
Background Managing hypertension in frail older patients is challenging. Several institutions
and organizations have published up-to-date hypertension guidelines suggesting frailty …

[HTML][HTML] L-Arginine improves cognitive impairment in hypertensive frail older adults

P Mone, A Pansini, SS Jankauskas… - Frontiers in …, 2022 - frontiersin.org
Cognitive impairment is a prevailing event in hypertensive patients and in frail older adults.
Endothelial dysfunction has been shown to underlie both hypertension and cognitive …

Tai Chi versus health education as a frailty intervention for community-dwelling older adults with hypertension

JN Kohn, JD Lobo, EA Troyer, G Ang, KL Wilson… - Aging clinical and …, 2023 - Springer
Background Frailty is associated with poor outcomes among older adults with hypertension
and complicates its pharmacological management. Here, we assessed whether 12-weeks of …

Syncope: new solutions for an old problem

G Rivasi, A Ungar, A Moya, M Brignole… - Polish Heart …, 2021 - journals.viamedica.pl
Syncope is a frequent event in the general population. Approximately 1%–2% of all
emergency department admissions are due to syncope and at least one-third of all people …

Prediabetes Increases the Risk of Frailty in Prefrail Older Adults With Hypertension: Beneficial Effects of Metformin

G Santulli, V Visco, F Varzideh, G Guerra… - …, 2024 - Am Heart Assoc
BACKGROUND: Prediabetes has garnered increasing attention due to its association with
cardiovascular conditions, especially hypertension, which heightens the risk of prefrailty and …

[HTML][HTML] Antihypertensive medication in frail older adults: a narrative review through a deprescribing lens

R Kraut, C Lundby, O Babenko, A Kamal… - American Heart Journal …, 2022 - Elsevier
Purpose of review The management of hypertension in frail older adults remains
controversial, as these patients are underrepresented in clinical trials and practice …