Allogeneic hematopoietic cell transplantation for adults with acute myeloid leukemia: myths, controversies, and unknowns

V Gupta, MS Tallman… - Blood, The Journal of the …, 2011 - ashpublications.org
Progress in the last decade has improved the understanding of leukemia biology. Molecular
markers in combinations with cytogenetics have improved the risk stratification of acute …

Myeloid sarcoma is associated with superior event‐free survival and overall survival compared with acute myeloid leukemia

AM Tsimberidou, HM Kantarjian, S Wen… - … Journal of the …, 2008 - Wiley Online Library
BACKGROUND. It is unknown whether patients with nonleukemic myeloid sarcoma (MS)
and those with acute myeloid leukemia (AML) have similar responses to anti‐AML treatment …

Acute myeloid leukemia and myelodysplastic syndromes in older adults

HD Klepin, AV Rao, TS Pardee - Journal of clinical oncology, 2014 - ascopubs.org
Treatment of older adults with acute myeloid leukemia (AML) or myelodysplastic syndromes
(MDS) is challenging because of disease morbidity and associated treatments. Both …

Impact of graft-versus-host disease after reduced-intensity conditioning allogeneic stem cell transplantation for acute myeloid leukemia: a report from the Acute …

F Baron, M Labopin, D Niederwieser, S Vigouroux… - Leukemia, 2012 - nature.com
This report investigated the impact of graft-versus-host disease (GVHD) on transplantation
outcomes in 1859 acute myeloid leukemia patients given allogeneic peripheral blood stem …

Acute myeloid leukaemia in the elderly: a review

DA Pollyea, HE Kohrt… - British journal of …, 2011 - Wiley Online Library
The majority of patients with acute myeloid leukaemia (AML) are elderly. Advancements in
supportive care and regimen intensification have resulted in improvements in clinical …

Molecular therapy for acute myeloid leukaemia

CC Coombs, MS Tallman, RL Levine - Nature reviews Clinical oncology, 2016 - nature.com
Acute myeloid leukaemia (AML) is a heterogeneous disease that is, in general, associated
with a very poor prognosis. Multiple cytogenetic and molecular abnormalities that …

Current and emerging therapies for acute myeloid leukemia

T Robak, A Wierzbowska - Clinical therapeutics, 2009 - Elsevier
Background: Acute myeloid leukemia (AML) is a clonal disease characterized by the
proliferation and accumulation of myeloid progenitor cells in the bone marrow, which …

Histone deacetylase inhibitors for the treatment of myelodysplastic syndrome and acute myeloid leukemia

A Quintas-Cardama, FPS Santos, G Garcia-Manero - Leukemia, 2011 - nature.com
Epigenetic changes have been identified in recent years as important factors in the
pathogenesis of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) …

Age is no barrier for adults undergoing HCT for AML in CR1: contemporary CIBMTR analysis

JE Maakaron, MJ Zhang, K Chen… - Bone marrow …, 2022 - nature.com
Abstract Acute Myeloid Leukemia (AML) has a median age at diagnosis of 67 years. The
most common curative therapy remains an allogeneic hematopoietic stem cell …

[HTML][HTML] Haploidentical transplantation for older patients with acute myeloid leukemia and myelodysplastic syndrome

SO Ciurea, MV Shah, RM Saliba, S Gaballa… - Biology of blood and …, 2018 - Elsevier
Allogeneic stem cell transplantation with HLA-matched donors is increasingly used for older
patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). It …