Challenges in treating older patients with acute myeloid leukemia
LD Eleni, ZC Nicholas, S Alexandros - Journal of oncology, 2010 - Wiley Online Library
Whereas in younger patients diagnosed with acute myeloid leukemia (AML) treatment is
straightforward and the goal is cure, the optimal treatment decision for older adults remains …
straightforward and the goal is cure, the optimal treatment decision for older adults remains …
Long term survival among patients who are disease free at 1-year post allogeneic hematopoietic cell transplantation: a single center analysis of 389 consecutive …
MM Solh, A Bashey, SR Solomon, LE Morris… - Bone Marrow …, 2018 - nature.com
Allogeneic hematopoietic cell transplantation (HCT) is associated with significant morbidity
and mortality especially in the first year after HCT. In this study, we examine the long-term …
and mortality especially in the first year after HCT. In this study, we examine the long-term …
Early matched sibling hematopoietic cell transplantation for adult AML in first remission using an age-adapted strategy: long-term results of a prospective GOELAMS …
B Lioure, MC Béné, A Pigneux, A Huynh… - Blood, The Journal …, 2012 - ashpublications.org
The LAM2001 phase 3 trial, involving 832 patients with acute myeloid leukemia (AML;
median: 46 years) proposed HLA-identical sibling allograft HSCT for all patients with an …
median: 46 years) proposed HLA-identical sibling allograft HSCT for all patients with an …
Long-term outcome of reduced-intensity allogeneic hematopoietic SCT in patients with AML in CR
U Popat, MJ De Lima, RM Saliba, P Anderlini… - Bone marrow …, 2012 - nature.com
A total of 36 consecutive patients with AML in CR underwent reduced-intensity allogeneic
hematopoietic SCT (RISCT) with fludarabine and melphalan conditioning. All patients were …
hematopoietic SCT (RISCT) with fludarabine and melphalan conditioning. All patients were …
Acute myeloid leukemia in the elderly: do we know who should be treated and how?
A Nazha, F Ravandi - Leukemia & lymphoma, 2014 - Taylor & Francis
Acute myeloid leukemia (AML) in the elderly is associated with several distinctive biological
and clinical features compared to younger patients. Despite the advances in supportive care …
and clinical features compared to younger patients. Despite the advances in supportive care …
[HTML][HTML] Allogeneic hematopoietic stem cell transplantation is underutilized in older patients with myelodysplastic syndromes
BM Getta, A Kishtagari, P Hilden, MS Tallman… - Biology of Blood and …, 2017 - Elsevier
Allogeneic hematopoietic stem cell transplantation (HCT) is the only curative treatment for
myelodysplastic syndrome (MDS). The proportion of MDS patients referred for …
myelodysplastic syndrome (MDS). The proportion of MDS patients referred for …
Prospective analysis to determine barriers to allogeneic hematopoietic cell transplantation in patients with acute leukemia
K Nath, J Lee, TA Elko, L Levy… - American Journal of …, 2023 - Wiley Online Library
Allogeneic hematopoietic cell transplantation (allo‐HCT) is a potentially curative treatment
for patients with acute leukemia. Despite this, studies have shown that only a minority of …
for patients with acute leukemia. Despite this, studies have shown that only a minority of …
[HTML][HTML] Umbilical cord blood transplantation outcomes in acute myelogenous leukemia/myelodysplastic syndrome patients aged≥ 70 years
KS Sandhu, C Brunstein, T DeFor, N Bejanyan… - Biology of Blood and …, 2016 - Elsevier
The maximum age of patients receiving allogeneic hematopoietic stem cell transplantation
(alloHCT) has been moving up over time. However, the availability of a suitable HLA …
(alloHCT) has been moving up over time. However, the availability of a suitable HLA …
Phase I/II study of gemtuzumab ozogamicin added to fludarabine, melphalan and allogeneic hematopoietic stem cell transplantation for high-risk CD33 positive …
We investigated the hypothesis that gemtuzumab ozogamicin (GO), an anti-CD33
immunotoxin would improve the efficacy of fludarabine/melphalan as a preparative regimen …
immunotoxin would improve the efficacy of fludarabine/melphalan as a preparative regimen …