Impaired wound healing in chronic wounds has been a significant challenge for clinicians
and researchers for decades. Traditional herbal medicine (THM) has a long history of …

Background and aims Diabetic foot ulcer (DFU) is one of the most common but uncontrolled
health issues of diabetic patients that needs more therapeutic considerations. This …

Despite the advancement in the treatment, nonhealing diabetic foot ulcers (DFUs) are an
important clinical issue accounting for increased morbidity and risk of amputation. Persistent …

Cutaneous Leishmaniasis (CL) is a tropical disease characterized by cutaneous ulcers,
sometimes with satellite lesions and nodular lymphangitis. Leishmania parasites …

Background Although the pathology and bacterial status of the “normal” bone stump after
operation of diabetic foot osteomyelitis (DFO) are of great significance for the prognosis of …

Background Non-surgical chronic wounds, including diabetes-related foot diseases (DRFD),
pressure injuries (PIs) and venous leg ulcers (VLU), are common hard-to-heal wounds …

Abstract Purpose of Review In 2019, the International Working Group on the Diabetic Foot
voiced six concerns regarding the use of molecular microbiology techniques for routine …

Polymicrobial biofilms provide a complex environment where co-infecting microorganisms
can behave antagonistically, additively, or synergistically to alter the disease outcome …

Identifying the microbiome within chronic diabetic foot ulcers is essential if effective
antimicrobial therapies are to be administered. Using culture and 16S rRNA gene …

Current microbiome investigations of patients with pressure ulcers (PU) are mainly based on
wound swabs and/or biopsy sequencing, leaving the colonization scenario unclear. Urinary …