Manifestations of human cytomegalovirus infection: proposed mechanisms of acute and chronic disease

W Britt - Human cytomegalovirus, 2008 - Springer
Infections with human cytomegalovirus (HCMV) are a major cause of morbidity and mortality
in humans with acquired or developmental deficits in innate and adaptive immunity. In the …

Quantitation of cytomegalovirus: methodologic aspects and clinical applications

M Boeckh, G Boivin - Clinical microbiology reviews, 1998 - Am Soc Microbiol
Cytomegalovirus (CMV) is an important pathogen in transplant recipients and human
immunodeficiency virus (HIV)-infected individuals. Major progress has been made in …

Overview of the diagnosis of cytomegalovirus infection

SA Ross, Z Novak, S Pati… - Infectious Disorders-Drug …, 2011 - ingentaconnect.com
Cytomegalovirus (CMV) is recognized as the most common congenital viral infection in
humans and an important cause of morbidity and mortality in immunocompromised hosts …

Optimization of quantitative detection of cytomegalovirus DNA in plasma by real-time PCR

M Boeckh, ML Huang, J Ferrenberg… - Journal of clinical …, 2004 - Am Soc Microbiol
Previous studies have shown that detection of cytomegalovirus (CMV) DNA in plasma is less
sensitive than the antigenemia assay for CMV surveillance in blood. In 1,983 blood samples …

Cytomegalovirus disease in the era of highly active antiretroviral therapy (HAART)

C Steininger, E Puchhammer-Stöckl… - Journal of Clinical …, 2006 - Elsevier
Cytomegalovirus (CMV) infection was one of the most important opportunistic infections in
HIV-infected patients before the introduction of highly active antiretroviral therapy (HAART) …

Human cytomegalovirus DNA in plasma and serum specimens of renal transplant recipients is highly fragmented

R Boom, CJA Sol, T Schuurman… - Journal of clinical …, 2002 - Am Soc Microbiol
Quantitation of cytomegalovirus (CMV) DNA in plasma and serum by PCR is increasingly
used to identify patients at risk for developing CMV disease and to monitor the efficacy of …

Automated extraction and quantification of human cytomegalovirus DNA in whole blood by real-time PCR assay

C Mengelle, K Sandres-Saune… - Journal of clinical …, 2003 - Am Soc Microbiol
The measurement of human cytomegalovirus (HCMV) DNA in blood is becoming the
standard method for monitoring HCMV infection in immune-suppressed and unsuppressed …

Multiplex, quantitative, real-time PCR assay for cytomegalovirus and human DNA

JL Sanchez, GA Storch - Journal of clinical microbiology, 2002 - Am Soc Microbiol
We created a multiplex, quantitative, real-time PCR assay that amplifies cytomegalovirus
(CMV) and human DNA in the same reaction tube, allowing for a viral load determination …

Plasma cytomegalovirus DNA, pp65 antigenaemia and a low CD4 cell count remain risk factors for cytomegalovirus disease in patients receiving highly active …

D Salmon-Céron, MC Mazeron, S Chaput, N Boukli… - Aids, 2000 - journals.lww.com
Plasma cytomegalovirus DNA, pp65 antigenaemia and a low CD4... : AIDS Plasma
cytomegalovirus DNA, pp65 antigenaemia and a low CD4 cell count remain risk factors for …

Dose-adjusted preemptive therapy for cytomegalovirus disease based on real-time polymerase chain reaction after allogeneic hematopoietic stem cell transplantation

T Mori, S Okamoto, R Watanabe, T Yajima… - Bone marrow …, 2002 - nature.com
We have prospectively evaluated the efficacy of real-time PCR-guided preemptive therapy
for CMV diseases in allogeneic hematopoietic stem cell transplant recipients with grades II …