[HTML][HTML] COVIDomics: The proteomic and metabolomic signatures of COVID-19

M Costanzo, M Caterino, R Fedele, A Cevenini… - International journal of …, 2022 - mdpi.com
Omics-based technologies have been largely adopted during this unprecedented global
COVID-19 pandemic, allowing the scientific community to perform research on a large scale …

[HTML][HTML] Coagulopathy and fibrinolytic pathophysiology in COVID-19 and SARS-CoV-2 vaccination

S Yamada, H Asakura - International Journal of Molecular Sciences, 2022 - mdpi.com
Coronavirus Disease 2019 (COVID-19) is caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) and is frequently complicated by thrombosis. In some cases of …

[HTML][HTML] Differential co-expression network analysis reveals key hub-high traffic genes as potential therapeutic targets for COVID-19 pandemic

A Hasankhani, A Bahrami, N Sheybani, B Aria… - Frontiers in …, 2021 - frontiersin.org
Background The recent emergence of COVID-19, rapid worldwide spread, and incomplete
knowledge of molecular mechanisms underlying SARS-CoV-2 infection have limited …

[HTML][HTML] Association between antidepressant use and ED or hospital visits in outpatients with SARS-CoV-2

BA Fritz, N Hoertel, EJ Lenze, F Jalali… - Translational …, 2022 - nature.com
Antidepressants have previously been associated with better outcomes in patients
hospitalized with COVID-19, but their effect on clinical deterioration among ambulatory …

[HTML][HTML] Antiviral and anti-inflammatory activities of fluoxetine in a SARS-CoV-2 infection mouse model

D Péricat, SA Leon-Icaza, M Sanchez Rico… - International Journal of …, 2022 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic continues to cause significant
morbidity and mortality worldwide. Since a large portion of the world's population is currently …

[HTML][HTML] Metabolomics as a powerful tool for diagnostic, pronostic and drug intervention analysis in COVID-19

C Bruzzone, R Conde, N Embade, JM Mato… - Frontiers in molecular …, 2023 - frontiersin.org
COVID-19 currently represents one of the major health challenges worldwide. Albeit its
infectious character, with onset affectation mainly at the respiratory track, it is clear that the …

[HTML][HTML] Metabolic alterations upon SARS-CoV-2 infection and potential therapeutic targets against coronavirus infection

P Chen, M Wu, Y He, B Jiang, ML He - Signal Transduction and …, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) caused by coronavirus SARS-CoV-2
infection has become a global pandemic due to the high viral transmissibility and …

[HTML][HTML] The effect of antidepressants on the severity of COVID-19 in hospitalized patients: A systematic review and meta-analysis

H Nakhaee, M Zangiabadian, R Bayati, M Rahmanian… - PloS one, 2022 - journals.plos.org
Introduction Clinical Depression and the subsequent low immunity is a comorbidity that can
act as a risk factor for the severity of COVID-19 cases. Antidepressants such as Selective …

[HTML][HTML] Marked elevations in lung and plasma ceramide in COVID-19 linked to microvascular injury

I Petrache, E Pujadas, A Ganju, KA Serban… - JCI insight, 2023 - ncbi.nlm.nih.gov
The pathogenesis of the marked pulmonary microvasculature injury, a distinguishing feature
of COVID-19 acute respiratory distress syndrome (COVID-ARDS), remains unclear …

[HTML][HTML] Implications of sphingolipid metabolites in kidney diseases

SK Mallela, S Merscher, A Fornoni - International journal of molecular …, 2022 - mdpi.com
Sphingolipids, which act as a bioactive signaling molecules, are involved in several cellular
processes such as cell survival, proliferation, migration and apoptosis. An imbalance in the …