Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) in cancer progression and metastasis
N Beauchemin, A Arabzadeh - Cancer and Metastasis Reviews, 2013 - Springer
The discovery of the carcinoembryonic antigen (CEA) as a tumor marker for colorectal
cancer some 50 years ago became the first step in the identification of a much larger family …
cancer some 50 years ago became the first step in the identification of a much larger family …
CEACAM1 structure and function in immunity and its therapeutic implications
The type I membrane protein receptor carcinoembryonic antigen-related cell adhesion
molecule 1 (CEACAM1) distinctively exhibits significant alternative splicing that allows for …
molecule 1 (CEACAM1) distinctively exhibits significant alternative splicing that allows for …
[HTML][HTML] The secretome profiling of a pediatric airway epithelium infected with hRSV identified aberrant apical/basolateral trafficking and novel immune modulating …
O Touzelet, L Broadbent, SD Armstrong… - Molecular & cellular …, 2020 - ASBMB
The respiratory epithelium comprises polarized cells at the interface between the
environment and airway tissues. Polarized apical and basolateral protein secretions are a …
environment and airway tissues. Polarized apical and basolateral protein secretions are a …
Serum CEACAM1 correlates with disease progression and survival in malignant melanoma patients
S Sivan, F Suzan, O Rona, H Tamar… - Journal of …, 2012 - Wiley Online Library
The search for melanoma biomarkers is crucial, as the incidence of melanoma continues to
rise. We have previously demonstrated that serum CEACAM1 (sCEACAM1) is secreted from …
rise. We have previously demonstrated that serum CEACAM1 (sCEACAM1) is secreted from …
[HTML][HTML] Mouse hepatitis virus receptor as a determinant of the mouse susceptibility to MHV infection
F Taguchi, A Hirai-Yuki - Frontiers in microbiology, 2012 - frontiersin.org
In this review, we report that the receptor of mouse hepatitis virus (MHV), carcinoembryonic
antigen-related cell adhesion molecule 1 (CEACAM1), is an important determinant of mouse …
antigen-related cell adhesion molecule 1 (CEACAM1), is an important determinant of mouse …
Soluble signal inhibitory receptor on leukocytes-1 is released from activated neutrophils by proteinase 3 cleavage
HJ von Richthofen, GHA Westerlaken… - The Journal of …, 2023 - journals.aai.org
Signal inhibitory receptor on leukocytes-1 (SIRL-1) is an immune inhibitory receptor
expressed on human granulocytes and monocytes that dampens antimicrobial functions. We …
expressed on human granulocytes and monocytes that dampens antimicrobial functions. We …
CEACAM1 in malignant melanoma: a diagnostic and therapeutic target
S Sapoznik, R Ortenberg, J Schachter… - Current Topics in …, 2012 - ingentaconnect.com
CEACAM1 adhesion molecule is broadly expressed, participates in pivotal cellular and
immunological processes and is involved in cancer. Originally identified as a tumor …
immunological processes and is involved in cancer. Originally identified as a tumor …
Alterations in the proteome of the NHERF1 knockout mouse jejunal brush border membrane vesicles
Na/H exchanger regulatory factor 1 (NHERF1) is a scaffold protein made up of two PDZ
domains and an ERM binding domain. It is in the brush border of multiple epithelial cells …
domains and an ERM binding domain. It is in the brush border of multiple epithelial cells …
[HTML][HTML] Engineering a CEACAM1 Variant with the Increased Binding Affinity to TIM-3 Receptor
Background: TIM-3 is an inhibitory receptor expressed in a variety of cells, including
dendritic cells, T-helper 1 lymphocytes, and natural killer cells. Binding of this protein to its …
dendritic cells, T-helper 1 lymphocytes, and natural killer cells. Binding of this protein to its …
Apical expression of human full‐length hCEACAM1‐4L protein renders the Madin Darby Canine Kidney cells responsive to lipopolysaccharide leading to TLR4 …
V Liévin‐Le Moal, I Beau, C Rougeaux… - Cellular …, 2011 - Wiley Online Library
CEACAM1 expressed by granulocytes and epithelial cells is recognized as a membrane‐
associated receptor by some Gram‐negative pathogens. Here we report a previously …
associated receptor by some Gram‐negative pathogens. Here we report a previously …