Brain–machine interfaces from motor to mood

MM Shanechi - Nature neuroscience, 2019 - nature.com
Brain–machine interfaces (BMIs) create closed-loop control systems that interact with the
brain by recording and modulating neural activity and aim to restore lost function, most …

[HTML][HTML] Macroscopic resting-state brain dynamics are best described by linear models

E Nozari, MA Bertolero, J Stiso, L Caciagli… - Nature biomedical …, 2024 - nature.com
It is typically assumed that large networks of neurons exhibit a large repertoire of nonlinear
behaviours. Here we challenge this assumption by leveraging mathematical models derived …

[HTML][HTML] Multi-scale neural decoding and analysis

HY Lu, ES Lorenc, H Zhu, J Kilmarx… - Journal of neural …, 2021 - iopscience.iop.org
Objective. Complex spatiotemporal neural activity encodes rich information related to
behavior and cognition. Conventional research has focused on neural activity acquired …

Modelling and prediction of the dynamic responses of large-scale brain networks during direct electrical stimulation

Y Yang, S Qiao, OG Sani, JI Sedillo… - Nature biomedical …, 2021 - nature.com
Direct electrical stimulation can modulate the activity of brain networks for the treatment of
several neurological and neuropsychiatric disorders and for restoring lost function. However …

Modeling behaviorally relevant neural dynamics enabled by preferential subspace identification

OG Sani, H Abbaspourazad, YT Wong, B Pesaran… - Nature …, 2021 - nature.com
Neural activity exhibits complex dynamics related to various brain functions, internal states
and behaviors. Understanding how neural dynamics explain specific measured behaviors …

Dynamical flexible inference of nonlinear latent factors and structures in neural population activity

H Abbaspourazad, E Erturk, B Pesaran… - Nature Biomedical …, 2024 - nature.com
Modelling the spatiotemporal dynamics in the activity of neural populations while also
enabling their flexible inference is hindered by the complexity and noisiness of neural …

Is the brain macroscopically linear? A system identification of resting state dynamics

E Nozari, MA Bertolero, J Stiso, L Caciagli… - arXiv preprint arXiv …, 2020 - arxiv.org
A central challenge in the computational modeling of neural dynamics is the trade-off
between accuracy and simplicity. At the level of individual neurons, nonlinear dynamics are …

[HTML][HTML] Multiscale low-dimensional motor cortical state dynamics predict naturalistic reach-and-grasp behavior

H Abbaspourazad, M Choudhury, YT Wong… - Nature …, 2021 - nature.com
Motor function depends on neural dynamics spanning multiple spatiotemporal scales of
population activity, from spiking of neurons to larger-scale local field potentials (LFP). How …

Modeling and dissociation of intrinsic and input-driven neural population dynamics underlying behavior

P Vahidi, OG Sani… - Proceedings of the …, 2024 - National Acad Sciences
Neural dynamics can reflect intrinsic dynamics or dynamic inputs, such as sensory inputs or
inputs from other brain regions. To avoid misinterpreting temporally structured inputs as …

Models of communication and control for brain networks: distinctions, convergence, and future outlook

P Srivastava, E Nozari, JZ Kim, H Ju, D Zhou… - Network …, 2020 - direct.mit.edu
Recent advances in computational models of signal propagation and routing in the human
brain have underscored the critical role of white-matter structure. A complementary …