The belief that the vertebrate brain functions normally without classical lymphatic drainage
vessels has been held for many decades. On the contrary, new findings show that functional …

Background: Sleep disturbances and disruption of the neural regulation of the sleep-wake
rhythm appear to be involved in the cellular and molecular mechanisms of cognitive decline …

Sleep perturbations including fragmented sleep with frequent night-time awakenings and
daytime naps are common in patients with Alzheimer's disease (AD), and these daily …

Sleep disorders have previously been connected with the neurodegenerative pathology of
Alzheimer's disease (AD) due to the aggregation of β-amyloid (Aβ) peptides and tau …

Background Cognitive function in patients with primary hyperparathyroidism (PHPT) may be
affected and be identified to have been linked to the level of parathyroid hormone (PTH) …

Multiple players are involved in the brain integrative action besides the classical neuronal
and astrocyte networks. In the past, the concept of complex cellular networks has been …

Alzheimer's disease (AD) still remains an enigma for researchers and clinicians. The onset
of AD is insidious, gradually progressive and multifactorial. The recent accumulated …

Object The relationship between sleep duration trajectories and cognitive decline remains
uncertain. This study aims to examine the connections between various patterns of sleep …

Sleep alleviates Alzheimer's disease (AD)-related neuropathological processes, whereas
sleep disturbance in AD patients is associated with elevated peripheral inflammatory …

Compared with other primates, humans sleep less and have a much higher prevalence of
Alzheimer's disease (AD) pathology. This article reviews evidence relevant to the hypothesis …