Functional DNA sensors integrated with nucleic acid signal amplification strategies for non-nucleic acid targets detection
Y Zhu, J Wu, Q Zhou - Biosensors and Bioelectronics, 2023 - Elsevier
In addition to carrying and transmitting genetic material, some DNA molecules have specific
binding ability or catalytic function. DNA with this special function is collectively referred to as …
binding ability or catalytic function. DNA with this special function is collectively referred to as …
Biomedical applications of DNA‐based hydrogels
J Gačanin, CV Synatschke… - Advanced Functional …, 2020 - Wiley Online Library
Nucleic acids are gaining significant attention as versatile building blocks for the next
generation of soft materials. Due to significant advances in the chemical synthesis and …
generation of soft materials. Due to significant advances in the chemical synthesis and …
Aptamer-integrated DNA nanostructures for biosensing, bioimaging and cancer therapy
The combination of nanostructures with biomolecules leading to the generation of functional
nanosystems holds great promise for biotechnological and biomedical applications. As a …
nanosystems holds great promise for biotechnological and biomedical applications. As a …
Rationally engineered nucleic acid architectures for biosensing applications
Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …
[HTML][HTML] Transformable liquid-metal nanomedicine
To date, numerous inorganic nanocarriers have been explored for drug delivery systems
(DDSs). However, the clinical application of inorganic formulations has often been hindered …
(DDSs). However, the clinical application of inorganic formulations has often been hindered …
Rolling circle amplification: a versatile tool for chemical biology, materials science and medicine
Rolling circle amplification (RCA) is an isothermal enzymatic process where a short DNA or
RNA primer is amplified to form a long single stranded DNA or RNA using a circular DNA …
RNA primer is amplified to form a long single stranded DNA or RNA using a circular DNA …
Bioinspired engineering of a multivalent aptamer‐functionalized nanointerface to enhance the capture and release of circulating tumor cells
Y Song, Y Shi, M Huang, W Wang… - Angewandte Chemie …, 2019 - Wiley Online Library
Circulating tumor cell (CTC)‐enrichment by using aptamers has a number of advantages,
but the issue of compromised binding affinities and stabilities in real samples hinders its …
but the issue of compromised binding affinities and stabilities in real samples hinders its …
Enhanced isolation and release of circulating tumor cells using nanoparticle binding and ligand exchange in a microfluidic chip
The detection of rare circulating tumor cells (CTCs) in the blood of cancer patients has the
potential to be a powerful and noninvasive method for examining metastasis, evaluating …
potential to be a powerful and noninvasive method for examining metastasis, evaluating …
Selection of DNA aptamers against epithelial cell adhesion molecule for cancer cell imaging and circulating tumor cell capture
Y Song, Z Zhu, Y An, W Zhang, H Zhang, D Liu… - Analytical …, 2013 - ACS Publications
Epithelial cell adhesion molecule (EpCAM) is overexpressed in most solid cancers and is an
ideal antigen for clinical applications in cancer diagnosis, prognosis, imaging, and therapy …
ideal antigen for clinical applications in cancer diagnosis, prognosis, imaging, and therapy …
Noncanonical self-assembly of multifunctional DNA nanoflowers for biomedical applications
DNA nanotechnology has been extensively explored to assemble various functional
nanostructures for versatile applications. Mediated by Watson–Crick base-pairing, these …
nanostructures for versatile applications. Mediated by Watson–Crick base-pairing, these …