Epithelial cell adhesion molecule (EpCAM) is overexpressed in most solid cancers and is an
ideal antigen for clinical applications in cancer diagnosis, prognosis, imaging, and therapy …

DNA nanotechnology has been extensively explored to assemble various functional
nanostructures for versatile applications. Mediated by Watson–Crick base-pairing, these …

We present a facile approach to make aptamer‐conjugated FRET (fluorescent resonance
energy transfer) nanoflowers (NFs) through rolling circle replication for multiplexed cellular …

Profiling the heterogeneous phenotypes of rare circulating tumour cells (CTCs) in whole
blood is critical to unravelling the complex and dynamic properties of these potential clinical …

In the past few years, with the in-depth research of functional nucleic acids and isothermal
amplification techniques, their applications in the field of biosensing have attracted great …

Smart biomaterials have the ability to respond to changes in physiological parameters and
exogenous stimuli and continue to impact many aspects of modern medicine. Smart …

Receptor–ligand interactions (RLIs) that play pivotal roles in living organisms are often
depicted with the classic keys-and-locks model. Nevertheless, RLIs on the cell surface are …

Aptamers are single-stranded DNA or RNA oligomers, identified from a random sequence
pool, with the ability to form unique and versatile tertiary structures that bind to cognate …

Rare cells are low-abundance cells in a much larger population of background cells.
Conventional benchtop techniques have limited capabilities to isolate and analyze rare cells …

Tumor-derived extracellular vesicles (T-EVs) represent valuable markers for tumor diagnosis
and treatment guidance. However, nanoscale sizes and the low abundance of marker …