Manipulating cell fate: dynamic control of cell behaviors on functional platforms

W Li, Z Yan, J Ren, X Qu - Chemical Society Reviews, 2018 - pubs.rsc.org
The cell microenvironment choreographs the behaviors of cells through multiple well-
controlled signals. For basic biological study and cell-based therapies, it is essential to …

[HTML][HTML] Expansion of CTCs from early stage lung cancer patients using a microfluidic co-culture model

Z Zhang, H Shiratsuchi, J Lin, G Chen, RM Reddy… - Oncotarget, 2014 - ncbi.nlm.nih.gov
The potential utility of circulating tumor cells (CTCs) to guide clinical care in oncology
patients has gained momentum with emerging micro-and nanotechnologies. Establishing …

Construction of rolling circle amplification products-based pure nucleic acid nanostructures for biomedical applications

C Li, Y Wang, PF Li, Q Fu - Acta Biomaterialia, 2023 - Elsevier
Nucleic acid nanomaterials with good biocompatibility, biodegradability, and
programmability have important applications in biomedical field. Nucleic acid nanomaterials …

Exosomes: isolation, analysis, and applications in cancer detection and therapy

H Bu, D He, X He, K Wang - Chembiochem, 2019 - Wiley Online Library
Exosomes are cell‐derived small extracellular vesicles that are naturally secreted by all
types of cells and widely distributed in various biofluids. They carry a variety of key bioactive …

Optical nano-biosensing interface via nucleic acid amplification strategy: construction and application

H Zhou, J Liu, JJ Xu, SS Zhang, HY Chen - Chemical Society Reviews, 2018 - pubs.rsc.org
Modern optical detection technology plays a critical role in current clinical detection due to
its high sensitivity and accuracy. However, higher requirements such as extremely high …

Multivalent duplexed-aptamer networks regulated a CRISPR-Cas12a system for circulating tumor cell detection

Z Lv, Q Wang, M Yang - Analytical Chemistry, 2021 - ACS Publications
Although circulating tumor cells (CTCs) have great potential to act as the mini-invasive liquid
biopsy cancer biomarker, a rapid and sensitive CTC detection method remains lacking …

[HTML][HTML] Recent progress in aptamer-based microfluidics for the detection of circulating tumor cells and extracellular vesicles

D Sun, Y Ma, M Wu, Z Chen, L Zhang, J Lu - Journal of Pharmaceutical …, 2023 - Elsevier
Liquid biopsy is a technology that exhibits potential to detect cancer early, monitor therapies,
and predict cancer prognosis due to its unique characteristics, including noninvasive …

Multivalent DNA nanospheres for enhanced capture of cancer cells in microfluidic devices

W Sheng, T Chen, W Tan, ZH Fan - ACS nano, 2013 - ACS Publications
Isolation of circulating tumor cells (CTCs) from peripheral blood or cancer cells from bone
marrow has significant applications in cancer diagnosis, therapy monitoring, and drug …

SpyLigase peptide–peptide ligation polymerizes affibodies to enhance magnetic cancer cell capture

JO Fierer, G Veggiani… - Proceedings of the …, 2014 - National Acad Sciences
Individual proteins can now often be modified with atomic precision, but there are still major
obstacles to connecting proteins into larger assemblies. To direct protein assembly, ideally …

Enrichment and single-cell analysis of circulating tumor cells

Y Song, T Tian, Y Shi, W Liu, Y Zou, T Khajvand… - Chemical …, 2017 - pubs.rsc.org
Up to 90% of cancer-related deaths are caused by metastatic cancer. Circulating tumor cells
(CTCs), a type of cancer cell that spreads through the blood after detaching from a solid …