Accurate and sensitive detection of rare cancer cells such as circulating tumor cells (CTCs)
has attracted great interest in the fields of clinical diagnosis and cancer research. However …

The targeted delivery of phytochemicals that promote energy expenditure for obesity therapy
remains a challenge. This study assembled a functionalized adipo-8 aptamer loaded with …

In this work, dynamic introduction of bioactive RGD peptide on a matrix was successfully
demonstrated via reversible multicovalent interactions within PBA/cis-diol polymeric …

The analysis of circulating tumor cells (CTCs) holds great significance for cancer diagnosis,
prognosis, and personalized therapy. However, the rarity, vulnerability and heterogeneity of …

Single cell analysis is of great significance to biological and biomedical research. With
recent development, lots of in situ amplification methods have been applied for imaging the …

Aptamer based microfluidic platforms have been developed rapidly in recent years, and
strategies to improve detection sensitivities of such platforms have attracted a significant …

Inorganic nanostructures have been used extensively to package nucleic acids into forms
useful for therapeutic applications. Here we report that the two products of transcription, RNA …

Exosomes are extracellular nanovesicles for transferring and delivering membrane and
cytosolic molecules between cells. Detection and profiling of exosomal proteins can provide …

Chemically functionalized and nanostructured materials, which mimic the features of the
natural extracellular matrix, provide a tool to organize cell surface receptors into nanoscale …

Cell-to-cell variation in gene expression creates a need for techniques that can characterize
expression at the level of individual cells. This is particularly true for rare circulating tumour …