Aberrant glycosylation is a key feature of malignant transformation. Hypersialylation, the
enhanced expression of sialic acid-terminated glycoconjugates on the cell surface, has …

Simple Summary Sialylation is a post-translational modification that consists in the addition
of sialic acid to growing glycan chains on glycoproteins and glycolipids. Aberrant sialylation …

Long non-coding RNAs (lncRNAs), which are important functional regulators in cancer, have
received increased attention in recent years. In this study, next-generation sequencing …

Simple Summary Cancer-associated glycosylation changes are widely used as biomarkers
and strongly impact malignancy. However, the clinical significance of the deranged …

Background Uterine corpus endometrial carcinoma (UCEC) is a gynecological malignant
tumor with low survival rate and poor prognosis. The traditional clinicopathological staging is …

Aims The biological functions of colorectal cancer (CRC) cell derived exosomes responding
to hypoxic microenvironment and its underlying mechanisms remain unclear. Main methods …

Glycosylation is a sophisticated informational system that controls specific biological
functions at the cellular and organismal level. Dysregulation of glycosylation may underlie …

The alterations of glycosylation, which is a common post-translational modification of
proteins, have been acknowledged as key events in breast cancer (BC) oncogenesis and …

In this review, the sugar portions of glycoproteins, glycolipids, and glycosaminoglycans
constitute the glycome, and the genes involved in their biosynthesis, degradation, transport …

Hepatocellular carcinoma (HCC) is one of the most lethal tumor types worldwide.
Glycosylation has shown promise in the study of tumor mechanisms and treatment. The …