Production of secondary metabolites using tissue culture-based biotechnological applications

II Ozyigit, I Dogan, A Hocaoglu-Ozyigit… - Frontiers in Plant …, 2023 - frontiersin.org
Plants are the sources of many bioactive secondary metabolites which are present in plant
organs including leaves, stems, roots, and flowers. Although they provide advantages to the …

Cannabis Bioactive Compound-Based Formulations: New Perspectives for the Management of Orofacial Pain

G Crescente, G Minervini, C Spagnuolo, S Moccia - Molecules, 2022 - mdpi.com
The management of orofacial pain to alleviate the quality of life of affected patients is
becoming increasingly challenging for scientific research and healthcare professionals …

[HTML][HTML] Research progress of therapeutic drugs for doxorubicin-induced cardiomyopathy

Y Chen, S Shi, Y Dai - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Doxorubicin (DOX), as a kind of chemotherapy agent with remarkable therapeutic effect, can
be used to treat diverse malignant tumors clinically. Dose-dependent cardiotoxicity is the …

Natural terpenoids with anti-inflammatory activities: Potential leads for anti-inflammatory drug discovery

J Ge, Z Liu, Z Zhong, L Wang, X Zhuo, J Li, X Jiang… - Bioorganic …, 2022 - Elsevier
Natural products are mainly secondary metabolites produced by plants, microorganisms,
and animals, which are still abundant in modern drug discovery. Terpenoids are the most …

Functionalized quinoxalinones as privileged structures with broad-ranging pharmacological activities

X Jiang, K Wu, R Bai, P Zhang, Y Zhang - European Journal of Medicinal …, 2022 - Elsevier
Quinoxalinones are a class of heterocyclic compounds which attract extensive attention
owing to their potential in the field of organic synthesis and medicinal chemistry. During the …

Phlorotannins–bioactivity and extraction perspectives

LRG Kumar, PT Paul, KK Anas, CS Tejpal… - Journal of Applied …, 2022 - Springer
Phlorotannins, a seaweed based class of polyphenolic compounds, have proven to possess
potential bioactivities such as antioxidant, antimicrobial, anti-allergic, anti-diabetic, anti …

Natural-derived alkaloids exhibit great potential in the treatment of ulcerative colitis

C Li, J Wang, R Ma, L Li, W Wu, D Cai, Q Lu - Pharmacological Research, 2022 - Elsevier
Ulcerative colitis (UC) is a chronic nonspecific inflammatory disease of colon and rectum
with unknown etiology, and the lesions are mainly confined to the mucosa and submucosa …

[HTML][HTML] Dendrobium officinale leaf polysaccharides regulation of immune response and gut microbiota composition in cyclophosphamide-treated mice

H Xie, J Fang, MA Farag, Z Li, P Sun, P Shao - Food Chemistry: X, 2022 - Elsevier
In this study, the polysaccharides extracted from Dendrobium officinale leaf (DOLP) was
used in immune deficiency mice to evaluate the bioactivity. Thymus and spleen indices were …

[HTML][HTML] Preparation methods, biological activities, and potential applications of marine algae oligosaccharides: A review

LX Zheng, Y Liu, S Tang, W Zhang… - Food Science and Human …, 2023 - Elsevier
Marine algae are valuable sources of health-promoting molecules that have been
consumed by Asians for decades. Among aquatic flora, marine algae stand out in terms of …

An overview of the biological evaluation of selected nitrogen-containing heterocycle medicinal chemistry compounds

O Ebenezer, MA Jordaan, G Carena, T Bono… - International Journal of …, 2022 - mdpi.com
Heterocyclic compounds are a class of compounds of natural origin with favorable
properties and hence have major pharmaceutical significance. They have an exceptional …