Brain lipidomics: From functional landscape to clinical significance

JH Yoon, Y Seo, YS Jo, S Lee, E Cho… - Science …, 2022 - science.org
Lipids are crucial components of cellular function owing to their role in membrane formation,
intercellular signaling, energy storage, and homeostasis maintenance. In the brain, lipid …

RONS and oxidative stress: An overview of basic concepts

AK Aranda-Rivera, A Cruz-Gregorio… - Oxygen, 2022 - mdpi.com
Oxidative stress (OS) has greatly interested the research community in understanding
damaging processes occurring in cells. OS is triggered by an imbalance between reactive …

Guidance on energy and macronutrients across the life span

SB Heymsfield, SA Shapses - New England Journal of Medicine, 2024 - Mass Medical Soc
Guidance on Energy and Macronutrients across the Life Span | New England Journal of Medicine
Skip to main content The New England Journal of Medicine homepage Advanced Search …

Porphyromonas gingivalis aggravates colitis via a gut microbiota-linoleic acid metabolism-Th17/Treg cell balance axis

L Jia, Y Jiang, L Wu, J Fu, J Du, Z Luo, L Guo… - Nature …, 2024 - nature.com
Periodontitis is closely related to inflammatory bowel disease (IBD). An excessive and non-
self-limiting immune response to the dysbiotic microbiome characterizes the two. However …

Lipid droplets and polyunsaturated fatty acid trafficking: Balancing life and death

M Danielli, L Perne, E Jarc Jovičić… - Frontiers in Cell and …, 2023 - frontiersin.org
Lipid droplets are fat storage organelles ubiquitously distributed across the eukaryotic
kingdom. They have a central role in regulating lipid metabolism and undergo a dynamic …

Promising sources of plant-derived polyunsaturated fatty acids: A narrative review

G Rizzo, L Baroni, M Lombardo - International Journal of Environmental …, 2023 - mdpi.com
(1) Background: Polyunsaturated fatty acids (PUFAs) are known for their ability to protect
against numerous metabolic disorders. The consumption of oily fish is the main source of …

Polyunsaturated fatty acids: conversion to lipid mediators, roles in inflammatory diseases and dietary sources

JL Harwood - International Journal of Molecular Sciences, 2023 - mdpi.com
Polyunsaturated fatty acids (PUFAs) are important components of the diet of mammals. Their
role was first established when the essential fatty acids (EFAs) linoleic acid and α-linolenic …

The role of α-linolenic acid and its oxylipins in human cardiovascular diseases

L Cambiaggi, A Chakravarty, N Noureddine… - International Journal of …, 2023 - mdpi.com
α-linolenic acid (ALA) is an essential C-18 n-3 polyunsaturated fatty acid (PUFA), which can
be elongated to longer n-3 PUFAs, such as eicosapentaenoic acid (EPA). These long-chain …

The effect of omega-3 fatty acids on sarcopenia: mechanism of action and potential efficacy

A Therdyothin, N Phiphopthatsanee, M Isanejad - Marine Drugs, 2023 - mdpi.com
Sarcopenia, a progressive disease characterized by a decline in muscle strength, quality,
and mass, affects aging population worldwide, leading to increased morbidity and mortality …

Protectins: Their biosynthesis, metabolism and structure-functions

TV Hansen, CN Serhan - Biochemical pharmacology, 2022 - Elsevier
Several lipoxygenase enzymes and cyclooxygenase-2 stereoselectively convert the
polyunsaturated fatty acids arachidonic acid, eicosapentaenoic acid, docosahexaenoic acid …